Evidence map›Paper›PMID 40314090›Full record

ArticleInternational journal of molecular medicine2025

miR‑34a induces apoptosis and pyroptosis in D‑Galactose‑induced aging cochlear hair cells via inhibiting TFAM and promoting mitochondrial dysfunction

Yilan Wang, Ming Yang, Guihua Wang, Weimin Liu, Bin Deng, Xiaoran Yang, Xuzhao Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yilan Wang *Department of Otolaryngology Head and Neck Surgery, People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, Yinchuan, Ningxia Hui 750002, P.R. China.
Ming Yang *Department of Emergency Medicine, People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, Yinchuan, Ningxia Hui 750002, P.R. China.
Guihua Wang *Department of Otolaryngology Head and Neck Surgery, People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, Yinchuan, Ningxia Hui 750002, P.R. China.
Weimin LiuDepartment of Otolaryngology Head and Neck Surgery, People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, Yinchuan, Ningxia Hui 750002, P.R. China.
Bin DengDepartment of Otolaryngology Head and Neck Surgery, People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, Yinchuan, Ningxia Hui 750002, P.R. China.
Xiaoran YangDepartment of Otolaryngology Head and Neck Surgery, People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, Yinchuan, Ningxia Hui 750002, P.R. China.
Xuzhao LiDepartment of General Surgery, People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, Yinchuan, Ningxia Hui 750002, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging of the auditory system causes progressive hearing deficit and affects millions of people; however, the underlying mechanism remains largely unknown. D‑galactose (D‑gal)‑induced aging models were established

Indexed as

AgingApoptosisDNA-Binding ProteinsGalactoseHair Cells, AuditoryMicroRNAsMitochondriaPyroptosisTranscription FactorsAnimalsCell LineHigh Mobility Group ProteinsMaleMiceMice, Inbred C57BLDNA-Binding ProteinsGalactoseHigh Mobility Group ProteinsMicroRNAsMIRN34a microRNA, mouseTfam protein, mouseTranscription Factorsage‑related hearing lossmicroRNA‑34amitochondrial dysfunctionmitochondrial transcription factor Apyroptosis

Identifiers

PMID40314090
PMCPMC12081035

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.