Evidence map›Paper›PMID 40313983›Full record

ArticlemLife2025

Leveraging collateral sensitivity to counteract the evolution of bacteriophage resistance in bacteria.

Yongqi Mu, Yuqin Song, Xueru Tian, Zixuan Ding, Shigang Yao, Yi Li, Chao Wang, Dawei Wei, Waldemar Vollmer, Gang Zhang and 1 more

Abstract read
In one paragraph

Article in mLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  3. Article
  4. mBio · 2026
    Article
  5. Review
  6. Article
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  8. Article
  9. Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yongqi MuState Key Laboratory of Microbial Resources, Institute of Microbiology Chinese Academy of Sciences Beijing China.
Yuqin SongState Key Laboratory of Microbial Resources, Institute of Microbiology Chinese Academy of Sciences Beijing China.
Xueru TianState Key Laboratory of Microbial Resources, Institute of Microbiology Chinese Academy of Sciences Beijing China.
Zixuan DingState Key Laboratory of Microbial Resources, Institute of Microbiology Chinese Academy of Sciences Beijing China.
Shigang YaoState Key Laboratory of Microbial Resources, Institute of Microbiology Chinese Academy of Sciences Beijing China.
Yi LiState Key Laboratory of Microbial Resources, Institute of Microbiology Chinese Academy of Sciences Beijing China.
Chao WangState Key Laboratory of Microbial Resources, Institute of Microbiology Chinese Academy of Sciences Beijing China.
Dawei WeiState Key Laboratory of Microbial Resources, Institute of Microbiology Chinese Academy of Sciences Beijing China.
Waldemar VollmerInstitute for Molecular Bioscience The University of Queensland Brisbane Queensland Australia.
Gang ZhangState Key Laboratory of Microbial Resources, Institute of Microbiology Chinese Academy of Sciences Beijing China.
Jie FengState Key Laboratory of Microbial Resources, Institute of Microbiology Chinese Academy of Sciences Beijing China.ORCID 0000-0001-5172-6643

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The escalating antibiotic resistance crisis poses a major global health threat. Bacteriophage therapy offers a promising alternative for combating multidrug-resistant infections. However, bacterial resistance to phages remains a significant hurdle. Innovative strategies are needed to overcome this challenge. In this study, we developed a phage cocktail based on our phage library, consisting of three phages that suppressed phage resistance of carbapenem-resistant hypervirulent

Indexed as

antibiotic resistancebacteriophage (phage) cocktailscollateral sensitivityevolutionKlebsiella pneumoniae

Identifiers

PMID40313983
PMCPMC12042119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.