ArticleResearch square2025
Immunity against reinfection in pigs following Taenia solium infection and a quantitative dose-response model.
Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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10 authors.
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Abstract
Background: Methods: This study investigates the effect of Results: No statistically significant differences in cyst counts were observed between pigs infected once and those that were reinfected, regardless of the initial dose (as low as 100 eggs) or reinfection dose (up to 20,000 eggs). This finding highlights that infection results in strong acquired immunity, effectively blocking subsequent infections. A quantitative dose-response model suggests that the relationship between egg dose and the number of viable cysts is best described by a power relationship. Combining data from single-infection and reinfected pigs into a unified model improved prediction precision. Finally, incorporating age at infection results in a model of the number of viable cysts in pigs depending on dose and age that combines acquired and innate immunity effects, i.e. changes in susceptibility with age. Conclusions: Initial exposure to
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