Evidence map›Paper›PMID 40313703›Full record

ArticleCentral European journal of urology2024

Benzodiazepines use and dependence in female patients with overactive bladder symptoms - prevalence and clinical correlations.

Artur Rogowski, Maria Krowicka-Wasyl, Bartosz Dybowski, Halina Sienkiewicz-Jarosz, Adam Wichniak, Jerzy Samochowiec, Marcin Wojnar, Tadeusz Issat, Tomasz Syrylo, Katarzyna Jankiewicz and 1 more

Abstract read
In one paragraph

Article in Central European journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Artur RogowskiDepartment of Minimally Invasive and Endoscopic Gynecology, Military Institute of Medicine, Legionowo, Poland.
Maria Krowicka-WasylDepartment of Obstetrics and Gynecology, Mother and Child Institute, Warsaw, Poland.
Bartosz DybowskiDepartment of Urology, Lazarski University, Warsaw, Poland.
Halina Sienkiewicz-Jarosz1 Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland.
Adam WichniakSleep Medicine Center and Third Department of Psychiatry, Institute of Psychiatry and Neurology, Warsaw, Poland.
Jerzy SamochowiecDepartment of Psychiatry, Pomeranian Medical University, Szczecin, Poland.
Marcin WojnarDepartment of Psychiatry, Medical University of Warsaw, Poland.
Tadeusz IssatDepartment of Obstetrics and Gynecology, Mother and Child Institute, Warsaw, Poland.
Tomasz SyryloDepartment of General, Oncological and Functional Urology, Military Institute of Medicine, Warsaw, Poland.
Katarzyna Jankiewicz2 Department of Gynecology, Medical University of Lublin, Poland.
Przemysław BieńkowskiDepartment of Psychiatry, Medical University of Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: GABAergic sedative-hypnotics, including benzodiazepines (BDZs) and Z-drugs, are some of the most used and misused psychotropic medications in developed countries. Growing evidence points to the role of psychiatric comorbidities in overactive bladder (OAB) and in urge urinary incontinence. The aim of the present study was to evaluate: 1) the prevalence of BDZs and/or Z-drugs use in female OAB patients, 2) the risk of dependence on BDZs and/or Z-drugs in female OAB patients, 3) the relationship between the use of BDZs and/or Z-drugs and the severity of OAB symptoms. Material and methods: The prevalence of BDZs and/or Z-drugs use, the risk of dependence on BDZs and/or Z-drugs, and the relationship between the use of BDZs and/or Z-drugs and the severity of OAB symptoms was assessed in OAB patients recruited in the urogynecological outpatient clinic. Results: A higher percentage of OAB patients confirmed the use of GABAergic sedative-hypnotics in the last 12 months as compared to the non-OAB outpatients presenting for routine gynecological prophylaxis. A larger number of OAB patients (5.6%) met the diagnosis of lifetime BDZ (and/or Z-drug) dependence as compared to the controls (0.9%). The use of sedative-hypnotics did not correlate with OAB symptoms. Conclusions: Our results suggest that the use of and dependence on GABAergic sedative-hypnotics may be associated with the OAB diagnosis in female urogynecological patients.

Indexed as

benzodiazepinesdependenceoveractive bladderurinary incontinenceurogynecologyuseZ-drugs

Identifiers

PMID40313703
PMCPMC12042402

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.