SynthesisFrontiers in medicine2025
Global research trends and basis of venous/lymphatic malformations during 2003-2023: a bibliometric study over two decades.
Synthesis in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Research trends and hotspots in sclerotherapy for vascular malformations: bibliometric and visual analyses.Frontiers in physiology · 2026Pooled it
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Venous/lymphatic malformations (VM/LM) represent a group of vascular anomalies that share similarities in diagnosis, classification, management, and pathogenesis. Despite growing research interest, no comprehensive bibliometric analysis has been conducted to map the knowledge landscape and evolution of VM/LM studies. Methods: We searched the Web of Science Core Collection database for VM/LM-related publications from January 2003 to December 2023. multiple analytical tools including VOSviewer, CiteSpace, and R package 'bibliometrix' were used to analyze publication trends, collaboration networks, and research hotspots. Results: 4,747 publications with 57,893 references were enrolled and analyzed. The number of publications is growing generally and erupted in 2019. The USA, China, and Japan are the top 3 countries in publication. The main study centers are scattered in the USA, Europe, China, and Japan. Fishman SJ published most. Vikkula M was cited most. Journal of Pediatric Surgery published and was cited most. The knowledge basis of VM/LM contains a wide range of concepts including classification/differential diagnosis, genetic causes, Sirolimus treatment, localized intravascular coagulopathy, and percutaneous treatment. The topic trend mainly changed after 2019 to genetic study and targeted therapy. Discussion: This is the first bibliometric analysis of VM/LM research demonstrating the field's rapid growth and shifting research hotspots. Four key future directions emerged: molecular-level diagnosis and classification, precision targeted therapy, advanced sclerotherapy techniques, and artificial intelligence applications. International collaboration between countries and centers needs to be strengthen. These findings provide an objective foundation for future VM/LM investigations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.