ArticleJournal of ophthalmology2025
Corneal Epithelial Defects in Diabetic Patients Following Pars Plana Vitrectomy.
Article in Journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
Diabetes mellitus is a known risk factor for corneal epithelial defects (CEDs) after pars plana vitrectomy (PPV), but it is unclear if diabetes severity or specific diabetic risk factors are associated with an increased risk of CED. The purpose of this retrospective cohort study was to identify factors associated with CED and healing time in association with diabetes severity in diabetic patients following PPV. The electronic health record database at University of Florida in Gainesville was queried to identify patients who underwent PPV for retinal detachment (RD) between April 2016 and April 2022. Patient charts were reviewed for clinical data including type of diabetes (if present), diabetes duration and severity, and associated diabetic comorbidities. The main outcome measures included presence of a CED within one month postoperatively, treatment of CED if present, and CED healing time. A total of 637 patients were analyzed, with a total of 243 eyes (26.5%) that belonged to diabetic patients. The diabetic patients were further separated into a proliferative diabetic retinopathy (PDR) group and a nonproliferative diabetic retinopathy (NPDR) group. Diabetes was associated with the development of an initial CED (
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