ArticleCureus2025
Long-Term Follow-Up of Omental Cranial Transposition to Bypass the Blood-Brain Barrier for Recurrent Glioblastoma: A Case Report and Scientific Rationale.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Extra-Abdominal Applications of the Greater Omentum in Canine and Feline Surgery: Current Knowledge, Surgical Techniques, and Clinical Perspectives.Animals : an open access journal from MDPI · 2026Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recurrent glioblastoma multiforme (GBM) is associated with a very poor prognosis due to the limited efficacy of existing therapies and constraints of blood-brain barrier (BBB) permeability. Particularly in the recurrent setting, there is no uniform standard of care treatment. In one of the proposed treatments for recurrent GBM, a laparoscopically harvested omental free tissue autograft is used to favor neovascularization and bypass the BBB, in which patients receive an autologous abdominal omental tissue intracranially following attempted gross total resection of the tumor. In this paper, we report the long-term survival and follow-up data of a patient who underwent this procedure. The progression-free and overall survival were 21 months and 30 months, respectively. We hypothesize that neovascularization from the omental flap helps bypass the BBB, and omental-derived autologous immune cells help penetrate the tumor microenvironment and recognize tumor-associated antigens, thus providing better tumor control for recurrent GBM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.