Evidence map›Paper›PMID 40313404›Full record

ArticleClinical medicine insights. Case reports2025

Periodontal Disease and Age-Related Maculopathy: A Case Report.

Francesco Mattia Ceruso, Stephany Gabriela Zambrano Leon, Luca Fiorillo, Gabriele Cervino, Marco Cicciù, Artak Heboyan, Francesco Pernice, Silvio Meloni, Marco Tallarico

Abstract readCase Reports
In one paragraph

Article in Clinical medicine insights. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Francesco Mattia CerusoDepartment of Dentistry "Fra G.B. Orsenigo" Ospedale San Pietro F.B.F, Rome, Italy.
Stephany Gabriela Zambrano LeonDepartment of Dentistry "Fra G.B. Orsenigo" Ospedale San Pietro F.B.F, Rome, Italy.
Luca FiorilloDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, Italy.ORCID https://orcid.org/0000-0003-0335-4165
Gabriele CervinoDepartment of Biomedical and Dental Sciences, Morphological and Functional Images, University of Messina, Italy.
Marco CicciùDepartment of General Surgery and Surgical-Medical Specialties, School of Dentistry, University of Catania, Italy.
Artak HeboyanDepartment of Prosthodontics, Faculty of Stomatology, Yerevan State Medical University after Mkhitar Heratsi, Armenia.ORCID https://orcid.org/0000-0001-8329-3205
Francesco PerniceDepartment of Dentistry "Fra G.B. Orsenigo" Ospedale San Pietro F.B.F, Rome, Italy.
Silvio MeloniDepartment of Medicine, Surgery, and Pharmacy, University of Sassari, Italy.
Marco TallaricoDepartment of Medicine, Surgery, and Pharmacy, University of Sassari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related macular degeneration (AMD) is a leading cause of significant vision impairment in individuals aged 50 and older, primarily impacting central vision. This study seeks to investigate potential associations between periodontal disease and age-related maculopathy in the analyzed clinical case. A male subject of 66 years old, with age-related degenerative maculopathy and severe periodontal disease, was evaluated and treated. After an initial phase of non-surgical causal periodontal therapy, the periodontal indices were re-evaluated. In addition, the extraction of hopeless teeth replaced by dental implants was performed. A retinal topography was used to assess possible regression of the pathology, and proper anti-VEGF therapy was administered. The results showed a regression of periodontal disease and an improvement of the degenerative maculopathy. These preliminary results, even if encouraging, should be supported by larger prospective trials.

Indexed as

age-related maculopathydental implantsmacular degenerationnon-surgical periodontal treatmentperiodontal diseases

Identifiers

PMID40313404
PMCPMC12044269

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.