Evidence map›Paper›PMID 40313246›Full record

ArticleFrontiers in oncology2025

Real-time tracking of lung tumors using a 1.5T Elekta Unity MR-Linac: first clinical experiences.

Blake Smith, Bryan Allen, Samuel Rusu, Joel St-Aubin, Daniel Hyer

Abstract read
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Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Blake SmithDepartment of Radiation Oncology, University of Iowa Health Care, Iowa City, Iowa, United States.
Bryan AllenDepartment of Radiation Oncology, University of Iowa Health Care, Iowa City, Iowa, United States.
Samuel RusuDepartment of Radiation Oncology, University of Iowa Health Care, Iowa City, Iowa, United States.
Joel St-AubinDepartment of Radiation Oncology, University of Iowa Health Care, Iowa City, Iowa, United States.
Daniel HyerDepartment of Radiation Oncology, University of Iowa Health Care, Iowa City, Iowa, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a growing interest in the application of MRI-guided adaptive radiotherapy (MRIgART) to improve the treatment of lung tumors. Motion management plays a central role to better localize these tumors and minimize toxicities to surrounding healthy tissue. Elekta recently released their comprehensive motion management system for the Unity 1.5T MR-Linac, enabling real-time tracking and predictive gating using MR cine imaging during treatment. We report our first clinical experiences using this gating technology to treat patients with central lung tumors adjacent to critical structures on the Unity MR-Linac using both conventional and SBRT fractionations. A surrogate structure was tracked if the primary target could not be visualized. Beam gating was automatically performed if the system detected the target moving outside of the defined gating envelope, which was set as the planning target volume. Integrating this technology has profoundly impacted our MRIgART program; we have been able to treat challenging lung tumor patients with greater precision and have begun to reduce our PTV margins, leading to improved dose sparing of nearby critical structures.

Indexed as

adaptivegatinglungmotion managementMR-Linac

Identifiers

PMID40313246
PMCPMC12044338

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.