Evidence map›Paper›PMID 40312957›Full record

ArticleInorganic chemistry2025

Cytotoxicity and Binding to DNA, Lysozyme, Ribonuclease A, and Human Serum Albumin of the Diiodido Analog of Picoplatin.

Giarita Ferraro, Jitka Pracharova, Giovanni Gotte, Lara Massai, Michal Berecka, Pavel Starha, Luigi Messori, Antonello Merlino

Abstract read
In one paragraph

Article in Inorganic chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giarita FerraroDepartment of Chemical Sciences, University of Naples Federico II, Complesso Universitario di Monte Sant'Angelo, via Cinthia 21, Naples 80126, Italy.
Jitka PracharovaDepartment of Biophysics, Faculty of Science, Palacký University Olomouc, Slechtitelu 27, Olomouc 783 71, Czech Republic.ORCID 0000-0001-7324-8347
Giovanni GotteDepartment of Neuroscience, Biomedicine, and Movement Sciences, Biological Chemistry Section, University of Verona, Strada Le Grazie 8, Verona I-37134, Italy.ORCID 0000-0003-3179-7158
Lara MassaiDepartment of Chemistry "Ugo Schiff", University of Florence, via della Lastruccia 3-13, Sesto Fiorentino 50019, Florence, Italy.ORCID 0000-0003-0765-1802
Michal BereckaDepartment of Biophysics, Faculty of Science, Palacký University Olomouc, Slechtitelu 27, Olomouc 783 71, Czech Republic.
Pavel StarhaDepartment of Inorganic Chemistry, Faculty of Science, Palacký University Olomouc, 17 listopadu 1192/12, Olomouc 771 46, Czech Republic.ORCID 0000-0003-0422-045X
Luigi MessoriDepartment of Chemistry "Ugo Schiff", University of Florence, via della Lastruccia 3-13, Sesto Fiorentino 50019, Florence, Italy.ORCID 0000-0002-9490-8014
Antonello MerlinoDepartment of Chemical Sciences, University of Naples Federico II, Complesso Universitario di Monte Sant'Angelo, via Cinthia 21, Naples 80126, Italy.ORCID 0000-0002-1045-7720

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we investigated cytotoxicity and DNA and protein binding of an iodido analog of picoplatin, the

Indexed as

Antineoplastic AgentsDNAMuramidaseOrganoplatinum CompoundsRibonuclease, PancreaticSerum Albumin, HumanBinding SitesCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorHumansMolecular StructureProtein BindingAntineoplastic AgentsDNAMuramidaseOrganoplatinum CompoundsRibonuclease, PancreaticSerum Albumin, Human

Identifiers

PMID40312957
PMCPMC12076543

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.