Evidence map›Paper›PMID 40312680›Full record

SynthesisBMC musculoskeletal disorders2025

Evaluating the effectiveness of six exercise interventions for low back pain: a systematic review and meta-analysis.

Mei Cheng, Yu Tian, Qi Ye, Jun Li, Lin Xie, Fan Ding

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mei ChengDepartment of Spinal Surgery, Wuhan Pu Ren Hospital, Wuhan, 430081, China.
Yu TianSports Medicine College, Wuhan Sports University, Wuhan, 430079, China.
Qi YeDepartment of Pediatric Rehabilitation Medicine, Wuhan No.9 Hospital, Wuhan, 430010, China.
Jun LiSchool of Medicine, Wuhan University of Science and Technology, Wuhan, 430081, China.
Lin XieDepartment of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. linxie@hust.edu.cn.
Fan DingDepartment of Spinal Surgery, Wuhan Pu Ren Hospital, Wuhan, 430081, China. Spine_dingfan@163.com.

Funding

Hubei Provincial Health Research Foundation WJ2021F015National Natural Science Foundation of China 82171490
6 · The paper itself

Abstract

objectiveTo validate the effectiveness of six exercise therapies in treating low back pain using Meta-analysis methods, and to propose optimal exercise duration, frequency, and cycle.

methodsDatabases such as PubMed, EMBASE, Cochrane Library, China National Knowledge Infrastructure, VIP Data, and SinoMed were searched. The RevMan 5.4 tool was utilized to conduct subgroup analyses on eight moderating variables, including types of exercise, duration, frequency, cycle, sample size, study quality, outcome indicator, and comparisons of different intervention methods with the control group from 42 included studies. Random effects models were employed to test for overall effects, heterogeneity, and bias.

resultsThe overall effect size for six exercise therapies for low back pain was significant (SMD= -1.21, P < 0.00001). Subgroup analyses showed yoga had the largest effect (SMD= -1.97, P = 0.0001). Exercise duration ≤ 30 min (SMD= -1.31, P < 0.0001), frequencies > 4 times/week (SMD= -1.56, P < 0.00001), and cycles ≤ 4 weeks (SMD= -1.61, P < 0.00001) were most effective. Sample sizes of 30~60 cases (SMD= -1.36, P < 0.00001) and studies with moderate bias risk (SMD= -1.37, P < 0.00001) also showed large effects. The Oswestry Disability Index scores demonstrated the most significant effect size (SMD= -3.35, P < 0.00001). The effect size of the physical factors in the control group was the largest (SMD= -1.85, P < 0.00001).

conclusionAll six exercise therapies effectively alleviated low back pain, with yoga showing the best results. The optimal exercise intervention protocol involved exercise duration not exceeding 30 min per session, frequency of more than 4 times per week, and cycle not exceeding 4 weeks. Additionally, exercise interventions exhibited the most significant improvements in Oswestry Disability Index scores for low back pain.

Indexed as

Exercise TherapyLow Back PainHumansTreatment OutcomeYogaEffect sizeExercise interventionLow back painMeta-analysisRandomized controlled trial

Identifiers

PMID40312680
PMCPMC12045001

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.