Evidence map›Paper›PMID 40312678›Full record

SynthesisBMC pediatrics2025

Effectiveness and safety of Tuina massage therapy for paediatric fever: a systematic review and meta-analysis of randomised controlled trials.

Di Liu, Tian-Yu Lin, Tian-Yuan Yu, Fan Wu, Ying-Qi Zhang, Jia-Yue Liu, Jia-Wei Sun, Han-Yu Zhang

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Di LiuSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, No. 11, Bei San Huan Dong Lu, Chaoyang District, Beijing, 102401, China.
Tian-Yu LinSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China.
Tian-Yuan YuSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, No. 11, Bei San Huan Dong Lu, Chaoyang District, Beijing, 102401, China. yutianyuan9@126.com.
Fan WuSpecial Education College of Beijing Union University, A1, Lane 2, Puhuangyu, Fengtai District, Beijing, 100075, China. wufan79523@outlook.com.
Ying-Qi ZhangSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, No. 11, Bei San Huan Dong Lu, Chaoyang District, Beijing, 102401, China.
Jia-Yue LiuSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, No. 11, Bei San Huan Dong Lu, Chaoyang District, Beijing, 102401, China.
Jia-Wei SunSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, No. 11, Bei San Huan Dong Lu, Chaoyang District, Beijing, 102401, China.
Han-Yu ZhangSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, No. 11, Bei San Huan Dong Lu, Chaoyang District, Beijing, 102401, China.

Funding

National Natural Science Foundation of China 81873392
6 · The paper itself

Abstract

objectiveTo systematically analyse the efficacy and safety of Tuina massage therapy for paediatric fever. METHODS AND

resultsA search was conducted across PubMed, Embase, Cochrane Central Register of Controlled Trials and China National Knowledge Infrastructure databases, and it retrieved relevant randomised controlled trials (RCTs) up to November 2023. Fifteen trials (1,661 pediatric patients) were included, focusing on Tuina massage and tepid water massage. Studies were excluded due to: duplicate data, irrelevant types, incomplete outcomes and use of other interventions. The Cochrane RoB tool was employed to assess methodological quality, and the GRADE approach was used to evaluate the certainty of evidence. The review was registered with the International Platform of Registered Systematic Review and Meta-analysis Protocols (INPLASY), registration number INPLASY202270041, following PRISMA 2020 guidelines. Massage treatment (120 min) showed a non-significant difference (standardized mean difference [SMD]: 0.68; 95% CI: - 0.31-1.67) compared with antipyretic medication. However, combining antipyretic medication and massage significantly reduced fever (SMD: 0.90; 95% CI: 0.50-1.30). Subgroup analysis indicated traditional Chinese Tuina massage significantly reduced pediatric fever (relative risk [RR]: 0.41; 95% CI: 0.26-0.65).

conclusionThis meta-analysis suggests that traditional Chinese Tuina may be a promising adjunctive therapy for pediatric fever. Careful consideration of each child's specific conditions is necessary to ensure safety and comfort. Future research should enhance study design quality and broaden the scope of non-pharmacological treatment methods.

Indexed as

FeverMassageAntipyreticsChildHumansRandomized Controlled Trials as TopicTreatment OutcomeAntipyreticsChildrenFeverMeta-analysisTuina massage

Identifiers

PMID40312678
PMCPMC12044972

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.