Evidence map›Paper›PMID 40312569›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

The effects of a 3-month walking and dietary education program on the quality of life of patients with esophageal cancer: a 1-year follow-up randomized controlled trial.

Hui-Mei Chen, Chien-Sheng Huang, Yu-Chung Wu, Ling-I Chien, Po-Kuei Hsu

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03161535 (Effectiveness of a Rehabilitation Program in Improving Sleep Quality, Emotional Distress, Circadian Rhythms, and Quality of Life in Patients With Esophageal Cancer), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03161535 naactive not recruitingnot on this map

Effectiveness of a Rehabilitation Program in Improving Sleep Quality, Emotional Distress, Circadian Rhythms, and Quality of Life in Patients With Esophageal Cancer

TypeinterventionalSponsorTaipei Veterans General Hospital, TaiwanRan2017 to 2026Enrolled85ConditionsEsophageal CancerArmsexercise and dietary education, weekly telephone consultations concerning exercise and diet.
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hui-Mei ChenSchool of Nursing, College of Nursing, National Taipei University of Nursing and Health Sciences, Mingde Rd, Office S307, No. 365, Beitou District, Taipei City, 112303, Taiwan. alice@ntunhs.edu.tw.ORCID http://orcid.org/0000-0003-3907-6646
Chien-Sheng HuangDivision of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei City, 112303, Taiwan.
Yu-Chung WuDivision of Thoracic Surgery, Department of Surgery, Taipei Medical University Hospital, Taipei City, 110301, Taiwan.
Ling-I ChienDepartment of Nursing, Taipei Veterans General Hospital, Taipei City, 112303, Taiwan.
Po-Kuei HsuDivision of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei City, 112303, Taiwan.

Funding

National Science and Technology Council NSTC 111-2314-B-227-005－
6 · The paper itself

Abstract

purposeTo examine the effects of a 12-week rehabilitation program of exercise combined with diet education on the quality of life (QOL) and symptoms (anxiety, depression, rest/activity circadian rhythm (RACR), and sleep) of patients with esophageal cancer.

methodsWe used a two-parallel-arms randomized controlled trial. The experimental group (EG) participated in a 12-week program involving walking exercise and diet education. The control group (CG) received standard care. The primary outcome was QOL, measured using the European Organisation for Research and Treatment of Cancer QOL core questionnaire (QLQ-C30) and esophageal module 18 (EORTC QLQ-OES18). Secondary outcomes were anxiety, depression, RACR, and sleep characteristics. Measurement time points were baseline and 3, 6, and 12 months after recruitment.

resultsOf 85 enrolled patients with esophageal cancer (EG = 43, CG = 42), the majority were male, 59 years old on average, and had received surgery. The EG recorded significantly better 24-h autocorrelation coefficient (0.06 to 0.24, p = 0.002; Cohen's d = 0.98) of rest/activity rhythms parameters at 6 months. In the EG, total sleep time significantly increased at 3 months (16.36 to 86.07, p = 0.004; Cohen's d = 0.86).

conclusionsThe intervention improved the RACR and sleep of patients with esophageal cancer. Healthcare professionals may consider incorporating this rehabilitation program into routine care alongside cancer treatment for patients with esophageal cancer. 

trial registrationClinicaltrials.gov (registration number: NCT03161535). Prospectively registered on 17 May 2017.

Indexed as

DietEsophageal NeoplasmsExercise TherapyPatient Education as TopicQuality of LifeWalkingAgedAnxietyCircadian RhythmDepressionFemaleFollow-Up StudiesHumansMaleMiddle AgedSurveys and QuestionnairesEsophageal NeoplasmsQuality of LifeRandomized Controlled TrialRehabilitationSigns and SymptomsSleep

Identifiers

PMID40312569

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.