Observational studyBMC psychiatry2025
Assessing comorbid PTSD, depression, and anxiety in fibromyalgia patients: a retrospective observational study.
Observational study in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Structural and Functional Neuroimaging Findings in Fibromyalgia: A Systematic Review.European journal of pain (London, England) · 2026Pooled it
- Kinesiophobia Level in Fibromyalgia Patients and Its Relationship with Cognitive Functions, Anxiety, Depression, Disease Activity and Pain Level.Healthcare (Basel, Switzerland) · 2026Article
- Sublingual Cyclobenzaprine: First Approval.Clinical drug investigation · 2026Review
- Alterations in cortical surface morphometry in fibromyalgia: a multi-parametric study.Frontiers in psychology · 2026Article
- [Digital treatment of fibromyalgia].Zeitschrift fur Rheumatologie · 2025Review
- A clinical study of ultrasound-guided acupotomy combined with mindfulness meditation to improve lumbar myofascial pain syndrome.Frontiers in neurology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFibromyalgia frequently coexists with psychiatric disorders, creating complex challenges in managing the health and quality of life for affected individuals. Existing literature points to significant overlap between fibromyalgia and conditions like posttraumatic stress disorder (PTSD), anxiety, and depression, but no large-scale analysis within a single American healthcare system has yet been conducted.
methodsThis retrospective observational study analyzed 1,516 fibromyalgia patients from HCA Healthcare facilities from January 1, 2022, to December 31, 2023, including only patients aged 18 and older with at least one psychiatric comorbidity. Chi-square tests examined associations between psychiatric outcomes (PTSD, depression, anxiety) and demographic factors such as age, sex, and race. Hospital length of stay (LOS) was analyzed among comorbidity groups using the Kruskal-Wallis test, with Bonferroni correction applied for pairwise comparisons.
resultsThe sample had a mean age of 52.2 years, was predominantly female (95.98%) and white (77.51%). Anxiety (61.02%) and depression (39.75%) were highly prevalent, while PTSD was less common (8.64%). Significant age differences emerged. Younger patients had more PTSD than those 65 + years old. Those 30-39 years old had the highest PTSD prevalence. Conversely, the prevalence of depression increased with age, peaking in the 65 + years old group. Anxiety was more prevalent in the middle-aged patients, peaking in the 40-52 years old group. White patients and nonwhite patients did not have significant differences in PTSD, anxiety, or depression prevalence. Sex differences were significant for anxiety only (p = .028), showing higher rates among females (62% in females versus 48% in males). Mean LOS was 1.93 days, with significant differences across comorbidity groups (p = < .0001). Pairwise comparisons revealed that patients with only anxiety tended to have significantly shorter LOS than patients with only depression and with two psychiatric comorbidities (p < .001).
conclusionsPsychiatric comorbidities are highly prevalent in hospitalized fibromyalgia patients and influence hospitalization outcomes. Anxiety, depression, and PTSD demonstrate unique relationships with age. The presence of multiple psychiatric comorbidities is associated with longer hospital stays, highlighting the need for integrated care approaches.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.