Evidence map›Paper›PMID 40312297›Full record

ArticleBMC gastroenterology2025

Visceral adiposity index as a predictor of metabolic dysfunction-associated steatotic liver disease: a cross-sectional study.

Tuo Zhou, Xiang Ding, Linjie Chen, Qianxiong Huang, Linfang He

Abstract read
In one paragraph

Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tuo ZhouDepartment of Gastroenterology, Yueyang Central Hospital, Yueyang, 414000, China.
Xiang DingDepartment of Gastroenterology, Yueyang Central Hospital, Yueyang, 414000, China.
Linjie ChenDepartment of Gastroenterology, Yueyang Central Hospital, Yueyang, 414000, China.
Qianxiong HuangDepartment of Gastroenterology, Yueyang Central Hospital, Yueyang, 414000, China.
Linfang HeDepartment of Gastroenterology, Yueyang Central Hospital, Yueyang, 414000, China. hlf060731@163.com.

Funding

Hunan Provincial Health Commission No.202203034641
6 · The paper itself

Abstract

backgroundThe association between visceral adiposity index (VAI) and metabolic dysfunction-associated steatotic liver disease (MASLD) remains unestablished. Our study sought to investigate the potential relationship between VAI and MASLD risk.

methodsThis study employed data from the 2017-2018 National Health and Nutrition Examination Survey (NHANES). Weighted multivariable regression models, subgroup analyses, and machine learning algorithms were used to evaluate associations and predictive performance.

resultsHigher VAI tertiles correlated with increased MASLD risk (adjusted OR for T3 vs. T1: 7.08, 95% CI: 4.35-11.5; P-trend=0.003). Machine learning models demonstrated robust predictive accuracy, with random forest (AUC=0.869) and gradient boosting machine (AUC=0.868) outperforming non-invasive scores. However, lipid accumulation product (LAP, AUC=0.834) and fatty liver index (FLI, AUC=0.833) achieved superior diagnostic performance compared to VAI (AUC=0.736), while maintaining clinical interpretability through simplicity and routine parameter availability.

conclusionsWhile VAI demonstrated significant positive associations with MASLD risk, non-invasive scores like LAP and FLI emerged as superior diagnostic tools, balancing accuracy with clinical practicality.

Indexed as

AdiposityFatty LiverIntra-Abdominal FatObesity, AbdominalAdultCross-Sectional StudiesFemaleHumansLipid Accumulation ProductMachine LearningMaleMiddle AgedNutrition SurveysPredictive Value of TestsRisk FactorsMachine learningMetabolic dysfunction-associated steatotic liver diseaseNational Health and Nutrition Examination SurveyNon-invasive scoresVisceral adiposity index

Identifiers

PMID40312297
PMCPMC12044771

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.