ArticleBMC plant biology2025
Integrated transcriptome and metabolome analysis revealed differential drought stress response mechanisms of wheat seedlings with varying drought tolerance.
Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Endophyte function in climate-stressed crops: integrating molecular regulation, metabolic trade-offs, and ecological constraints.Plant signaling & behavior · 2026Review
- Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
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- Integrative Physiological, Transcriptomic, and Functional Analysis Reveals a Positive Contribution ofGenes · 2026Article
- Integrated Transcriptomic and Metabolomic Analysis Reveals Molecular Responses Associated with Foliar Selenium Treatment Under Cold Stress in Rapeseed (International journal of molecular sciences · 2026Article
- Integrative transcriptional regulatory networks governing cereal root responses to heavy metals and drought.Plant cell reports · 2026Review
- Multi-Omics Dissection of Drought Stress Responses in Crops: From Molecular Regulatory Networks to Climate-Resilient Breeding Applications.International journal of molecular sciences · 2026Review
- Deciphering the genetic basis of wheat germination under ZnO nano priming and drought stress through integrated QTL mapping and network analyses.BMC plant biology · 2026Article
- Molecular basis of drought tolerance in Rosa xanthina: an integrated analysis of physiology, transcriptome, and NAC transcription factor.BMC genomics · 2026Article
- Article
- Mechanistic Analysis of Physiological and Metabolic Responses in Non-Jointed Water Dropwort Under Phosphorus Stress.Metabolites · 2026Article
- Metabolomic Profiling of Native Yucatan Maizes (Journal of agricultural and food chemistry · 2026Article
- Tissue-specific metabolomic profiling reveals cultivar-dependent drought tolerance mechanisms in rice (Oryza sativa L.).BMC plant biology · 2026Article
- Integrative physiological and transcriptomic analysis reveals drought response mechanisms in Abrus mollis Hance.BMC plant biology · 2026Article
- Genome-wide association study and gene network analysis of drought tolerance in wheat during early growth.Frontiers in plant science · 2026Article
- Genetic enhancement of root, tuber and cereal crops via pangenomics, multi-omics integration and AI-driven prediction.Frontiers in plant science · 2026Review
- Multiomics Profiling Unveils Key Genes and Metabolites Involved in the Salt Tolerance ofGenes · 2025Article
- A Review of Differential Plant Responses to Drought, Heat, and Combined Drought + Heat Stress.Current issues in molecular biology · 2025Review
- Chromosome-level genome assembly of Albizia odoratissima and effect of flavonoid metabolic pathways under drought stress.BMC plant biology · 2025Article
- Physiological and molecular mechanism analysis of Cyclocodon lancifolius seedlings in response to varying degrees of drought stress.BMC plant biology · 2025Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundWheat (Triticum aestivum L.) is a staple crop frequently enduring drought stress, significantly impacting its quantity and quality. Therefore, elucidating the underlying mechanisms of wheat's drought stress response is crucial for developing drought-tolerant varieties through molecular breeding techniques.
resultsThis study analyzed the transcriptome and metabolome of wheat seedlings with varying drought tolerance (drought-tolerant T13, control CK, and drought-susceptible T2) under drought stress. Results suggested that T13 and T2 had partially similar drought stress response mechanisms. But the mainly drought response mechanisms in T13 (accumulated flavonoids and phenolic acids) was different from T2 (accumulated alkaloids). Integrated metabolome and transcriptome analyses demonstrated significant up-regulation of most flavonoids and phenolic acids biosynthesis-related metabolites and genes (HCT, FLS, CHS and F3'5'H) in T13 under drought stress.
conclusionsThese results indicated that flavonoids and phenolic acids metabolisms were associated with wheat seedling's drought resistance, with their biosynthesis-related differentially expressed metabolites and genes possibly being key factors underlining the difference in drought tolerance. Thus this study enhances our understanding of wheat seedling's drought response mechanism, providing valuable insights for breeding drought-tolerant wheat cultivars.
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