Evidence map›Paper›PMID 40311848›Full record

ArticleClinical medicine (London, England)2025

Incidence of gestational diabetes in pregnant women with a history of bariatric surgery using a service evaluation.

B Jenner, D Jones, L C Kusinski, C Patient, A Park, A Sarker, V Bansiya, E M Gurnell, C L Meek

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Article in Clinical medicine (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

B JennerDepartment of Clinical Pharmacology and Therapeutics, Cambridge University NHS Foundation Trust, Cambridge, UK.
D JonesInstitute of Metabolic Science Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.
L C KusinskiInstitute of Metabolic Science Metabolic Research Laboratories, University of Cambridge, Cambridge, UK; Leicester Diabetes Centre and Leicester NIHR Biomedical Research Centre, University of Leicester, Leicester, UK.
C PatientCambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
A ParkCambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
A SarkerCambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
V BansiyaCambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
E M GurnellCambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
C L MeekInstitute of Metabolic Science Metabolic Research Laboratories, University of Cambridge, Cambridge, UK; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK; Leicester Diabetes Centre and Leicester NIHR Biomedical Research Centre, University of Leicester, Leicester, UK. Electronic address: cm881@leicester.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPregnant women with previous bariatric surgery are at increased risk of gestational diabetes mellitus (GDM) but many cannot safely tolerate the oral glucose tolerance test (OGTT). Consensus recommendations advise self-monitoring of blood glucose (SMBG) for GDM diagnosis, but diagnostic thresholds are unexplored in this population. STUDY

objectiveTo assess the incidence of SMBG-defined GDM (fasting, 1-hr postprandial thresholds: 90, 140 mg/dL (5.3, 7.8 mmol/L)) after bariatric surgery, compared to the incidence of OGTT-defined GDM in women with risk factors for GDM but no history of bariatric surgery. DESIGN AND

settingPatients with a history of bariatric surgery (n=24) were included in a retrospective service evaluation based at a single tertiary referral centre in England, with results compared to a national study of women at high risk of GDM but without a history of bariatric surgery (n=1,308).

main outcome measuresThe incidence of GDM diagnosed according to SMBG vs OGTT.

resultsGDM incidence was 16/24 (66.7%; SMBG-defined) after bariatric surgery and 121/1,308 (9.3%; OGTT-defined) in the control group, with the highest incidence rates seen after gastric bypass (85.7%). In women with previous bariatric surgery, HbA1c showed no association with GDM diagnosis, the requirement for treatment or offspring birth weight.

conclusionsSMBG at standard thresholds is not able to reliably diagnose GDM after bariatric surgery and is likely to over-diagnose GDM, especially after gastric bypass, although small sample size limits generalisability of this study. Alternative diagnostic and prognostic markers are warranted for diagnosis of GDM after bariatric surgery.

Indexed as

Bariatric SurgeryDiabetes, GestationalAdultBlood GlucoseBlood Glucose Self-MonitoringEnglandFemaleGlucose Tolerance TestHumansIncidencePregnancyRetrospective StudiesRisk FactorsBlood GlucoseBariatric surgeryCapillary glucose testingGestational diabetesObesityOral glucose tolerance testOverweightPregnancy

Identifiers

PMID40311848
PMCPMC12144429

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