Evidence map›Paper›PMID 40311748›Full record

ArticleThe Journal of thoracic and cardiovascular surgery2025

Long-term outcomes of isolated tricuspid surgery in 3706 patients: Implications for the future.

Shruthi Nammalwar, Derrick Y Tam, Sundos Alabbadi, Allen A Razavi, Aminah Sallam, Irsa Hasan, Dominic Emerson, Michael E Bowdish, Natalia Egorova, Joanna Chikwe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of thoracic and cardiovascular surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shruthi NammalwarDepartment of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, Calif.
Derrick Y TamDepartment of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, Calif.
Sundos AlabbadiDepartment of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY.
Allen A RazaviDepartment of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, Calif.
Aminah SallamDepartment of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, Calif.
Irsa HasanDepartment of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, Calif.
Dominic EmersonDepartment of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, Calif.
Michael E BowdishDepartment of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, Calif.
Natalia EgorovaDepartment of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY.
Joanna ChikweDepartment of Cardiac Surgery, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, Calif. Electronic address: Joanna.Chikwe@cshs.org.

Funding

Training in Advanced Heart Disease ResearchT32HL116273 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI Joshua I Goldhaber, EDUARDO MARBAN · 2013 to 2026
$5.6M
NHLBI NIH HHS T32 HL116273
6 · The paper itself

Abstract

objectivesEarly and late outcomes of isolated tricuspid surgery in contemporary practice are poorly defined. This statewide analysis evaluated the early and late outcomes of isolated tricuspid repair and replacement.

methodsFrom the Department of Health Care Access and Information of California State admissions database, 3706 patients who underwent isolated tricuspid repair (2419, 65.3%) or replacement (1287, 34.7%) between 1991 and 2020 were identified. Propensity score matching to adjust for 25 differences in baseline characteristics yielded 789 well-matched pairs. The primary outcome was all-cause mortality compared using Cox proportional hazards. The cumulative incidence of tricuspid reoperation and permanent pacemaker were compared in the Fine-Gray model with death as a competing risk. Median follow-up was 4.4 years (range, 0-30 years).

resultsIsolated tricuspid operations increased from 48 in 1991 to 207 in 2021 (P < .001). Patients undergoing repair were similar in age (53.5 vs 54.5 years, P = .17), more often men (44% vs 40% P = .03), and less likely to have endocarditis (21.5% vs 26.8%, P = .002) compared with patients undergoing replacement. Operative mortality was similar between repair and replacement (8.2% vs 9.9%, P = .27), whereas pacemaker rates were higher after replacement (13.7% vs 32.3%, P < .001). Tricuspid repair was associated with reduced mortality at 25 years compared with replacement (58.1% vs 65.5%; hazard ratio, 0.81, 95% CI, 0.70-0.94, P = .005). The cumulative incidence of reoperation was lower with repair (5.6% vs 11.1%, hazard ratio, 0.57, 95% CI, 0.37-0.88, P = .01).

conclusionsTricuspid valve repair is associated with superior early and late outcomes compared with replacement in a statewide administrative dataset.

Indexed as

Heart Valve Prosthesis ImplantationTricuspid ValveAdultAgedCaliforniaDatabases, FactualFemaleHumansMaleMiddle AgedPostoperative ComplicationsReoperationRetrospective StudiesRisk AssessmentRisk FactorsTime Factorspopulation-level datatricuspid regurgitationtricuspid valve surgery

Identifiers

PMID40311748
PMCPMC13110800

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.