Evidence map›Paper›PMID 40311672›Full record

ArticleThe Canadian journal of cardiology2025

Application of the Updated Cardiogenic Shock Working Group SCAI Classification for Cardiogenic Shock: A Single-Centre Analysis.

Monte Scott, Christos P Kyriakopoulos, Eric Sheffield, Ethan Krauspe, Konstantinos Sideris, Iosif Taleb, Eleni Maneta, Eleni Tseliou, Sean Selko, Rana Hamouche and 9 more

Abstract read
In one paragraph

Article in The Canadian journal of cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Monte ScottDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA. Electronic address: https://twitter.com/Scott.
Christos P KyriakopoulosDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA. Electronic address: https://twitter.com/Kyriakopoulos.
Eric SheffieldDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA.
Ethan KrauspeDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA. Electronic address: https://twitter.com/Krauspe.
Konstantinos SiderisDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA.
Iosif TalebDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA.
Eleni ManetaDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA.
Eleni TseliouDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA.
Sean SelkoDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA.
Rana HamoucheDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA.
Jake AadlandDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA.
Spencer J CarterDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA.
Tara L JonesDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA.
Zhining OuDivision of Epidemiology, Department of Internal Medicine, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA.
Angela P PressonDivision of Epidemiology, Department of Internal Medicine, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA.
Craig H SelzmanDivision of Cardiothoracic Surgery, Department of Surgery, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA.
Joseph E TonnaDivision of Cardiothoracic Surgery, Department of Surgery, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA.
Thomas C HanffDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA. Electronic address: https://twitter.com/Hanff.
Stavros G DrakosDivision of Cardiovascular Medicine, Department of Internal Medicine, University of Utah Health and School of Medicine, Salt Lake City, Utah, USA. Electronic address: stavros.drakos@hsc.utah.edu.

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
TRAINING IN CARDIOVASCULAR RESEARCHT32HL007576 · NHLBI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Stavros George Drakos, Robin M Shaw · 1985 to 2026
$10.6M
Clinical and Metabolic Signature of Recovered Myocardium in Human Heart FailureR01HL135121 · NHLBI · UNIVERSITY OF UTAH · PI DRAKOS, STAVROS GEORGE · 2017 to 2021
$1.9M
Cellular Remodeling in Heart Failure and after LVAD UnloadingR01HL132067 · NHLBI · UNIVERSITY OF UTAH · PI DRAKOS, STAVROS GEORGE, SACHSE, FRANK BERND · 2017 to 2020
$1.5M
CSRD VA I01 CX002291NCATS NIH HHS UL1 TR002538NHLBI NIH HHS R01 HL132067NHLBI NIH HHS R01 HL135121NHLBI NIH HHS T32 HL007576
6 · The paper itself

Abstract

backgroundIn 2019, the Society for Cardiovascular Angiography and Interventions (SCAI) proposed an algorithm to assess cardiogenic shock (CS) severity, known as SCAI classification. In 2022, the Cardiogenic Shock Working Group (CSWG) modified the original classification using specific parameters to better define hypotension and hypoperfusion with the goal to further refine stratification.

methodsConsecutive patients with CS who were managed at a quaternary academic medical centre from May 2015 to December 2021 were evaluated (N = 1162). Our study cohort comprised patients who developed CS after admission. In-hospital mortality per SCAI stage at shock onset was assessed. The percentages of temporary mechanical circulatory support use per SCAI stage at shock onset was also reported. In our study, we included intra-aortic balloon pump, percutaneous ventricular assist device, and venoarterial extracorporeal membrane oxygenation.

resultsOur study cohort comprised 742 patients with a median age of 62.0 (interquartile range, 51-72) years, mostly men (66%). Etiology of CS included 25% acute myocardial infarction and 75% non-acute myocardial infarction. In-hospital mortality per CS severity stage using the SCAI-CSWG classification was 14.30% for stage B, 20.90% for stage C, 32.70% for stage D, and 44.80% for stage E, whereas temporary mechanical circulatory support use was greatest in SCAI stage E.

conclusionsWe identified a direct relationship of in-hospital mortality per CS severity stage using the SCAI-CSWG classification in the overall cohort. These findings require further validation in prospective studies.

Indexed as

Shock, CardiogenicAgedAlgorithmsExtracorporeal Membrane OxygenationFemaleHeart-Assist DevicesHospital MortalityHumansIntra-Aortic Balloon PumpingMaleMiddle AgedRetrospective StudiesSeverity of Illness Index

Identifiers

PMID40311672
PMCPMC13477381

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.