ArticleEuropean journal of dentistry2025
Antimicrobial and Antibiofilm Properties of Hydroxyapatite/Nano-Hydroxyapatite in Preventing Dental Caries: A Systematic Review.
Article in European journal of dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Multifunctional Xanthan Gum-Hydroxyapatite Composite with Enhanced Dye Adsorption, Antibacterial Activity, and Cytocompatibility.Materials (Basel, Switzerland) · 2026Article
- In vitro evaluation of a novel self-adhesive composite primer modified with nano zinc oxide and hydroxyapatite: antibacterial activity, marginal microleakage, and interfacial elemental analysis.BMC oral health · 2026Article
- Biogenic nanohydroxyapatite derived from Channa striata fish bones using alkaline hydrolysis and calcination.Scientific reports · 2026Article
- Eggshell waste derived nano-hydroxyapatite/metakaolin composites for bone scaffold applications.RSC advances · 2026Article
- Personalized dentistry: Enhancing outcomes through patient-centered innovation.Bioinformation · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Controlling biofilm is a crucial strategy and an essential component of preventing dental caries. Considerable research has been conducted in recent years on the clinical application of hydroxyapatite (HAp) and hydroxyapatite nanoparticles (nHAp) in preventing dental caries. However, these studies have yet to investigate the effectiveness or mechanism of these substances as antibacterial and antibiofilm agents. This study aimed to provide a thorough analysis of the current evidence on the antibacterial and antibiofilm characteristics of HAp/nHAp in the prevention of dental caries. Searches were conducted across five databases: Cochrane Library, PubMed, Scopus, EBSCOhost, and ScienceDirect. Google Scholar was also searched. Titles, abstracts, and full text were evaluated following the guidelines set by the Preferred Reporting Item for Systematic Review and Meta-Analyses (PRISMA). A methodological quality assessment of the studies was conducted using the QUIN tool. The initial retrieval totaled 15,047 studies, from which 3,487 were excluded. A total of 11,560 studies were screened based on the title and abstract, resulting in 24 full-text studies considered potentially eligible for inclusion (
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.