Evidence map›Paper›PMID 40311126›Full record

ArticleJMIR human factors2025

Adapting a Text Messaging Intervention to Improve Diabetes Medication Adherence in a Spanish-Speaking Population: Qualitative Study.

Jacqueline Seiglie, Seth Tobolsky, Ricaurte Crespo Trevino, Lluvia Cordova, Sara Cromer, A Enrique Caballero, Margarita Alegria, J Jaime Miranda, Deborah Wexler, Lindsay Mayberry

Abstract read
In one paragraph

Article in JMIR human factors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jacqueline SeiglieDepartment of Medicine, Harvard Medical School, Boston, MA, United States.ORCID 0000-0001-9278-4516
Seth TobolskyDiabetes Unit, Massachusetts General Hospital, 50 Staniford St, Suite 340, Boston, MA, 02114, United States, 1 6177268722, 1 6177248534.ORCID 0000-0001-6530-5807
Ricaurte Crespo TrevinoMass General Brigham Salem Hospital, Salem, MA, United States.ORCID 0000-0001-8553-1617
Lluvia CordovaDiabetes Unit, Massachusetts General Hospital, 50 Staniford St, Suite 340, Boston, MA, 02114, United States, 1 6177268722, 1 6177248534.ORCID 0009-0000-4314-8353
Sara CromerDepartment of Medicine, Harvard Medical School, Boston, MA, United States.ORCID 0000-0002-4924-2049
A Enrique CaballeroDivision of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, MA, United States.ORCID 0000-0002-9957-3321
Margarita AlegriaDisparities Research Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.ORCID 0000-0003-2241-707X
J Jaime MirandaSydney School of Public Health, Faculty of Medicine and Health, University of Sydney, Sydney, Camperdown, Australia.ORCID 0000-0002-4738-5468
Deborah Wexler *Department of Medicine, Harvard Medical School, Boston, MA, United States.ORCID 0000-0001-6979-402X
Lindsay Mayberry *Vanderbilt University Medical Center, Nashville, TN, United States.ORCID 0000-0002-0654-4151

Funding

TRAINING PROGRAM IN ENDOCRINOLOGY AND DIABETEST32DK007028 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Karen K Miller · 1986 to 2026
$18.5M
REACH-Es: Adapting a digital health tool to improve diabetes medication adherence among Latino adultsK23DK135798 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Jacqueline Anne Seiglie · 2023 to 2026
$784k
NIDDK NIH HHS K23 DK135798NIDDK NIH HHS T32 DK007028
6 · The paper itself

Abstract

Background: Latino adults with type 2 diabetes (T2D) have higher rates of diabetes medication nonadherence than non-Hispanic White adults. REACH (Rapid Encouragement/Education And Communications for Health) is a text message platform based on the information-motivation-behavioral skills model that addresses barriers to adherence and was shown to improve adherence and glycated hemoglobin (HbA1c) levels, but it is only available in English. Objective: This study aimed to report the multiphase, stakeholder-driven adaptation of the REACH barriers to diabetes medication adherence content to a Latino population (REACH-Español). Methods: This was a qualitative study using focus groups. We identified potentially eligible patients (≥18 y old, Latino ethnicity, Spanish-language preference, and T2D diagnosis) using a Mass General Brigham Hospital query. Eligible patients were invited to participate in a focus group conducted in Spanish between April 13 and November 9, 2023. A total of 5 focus groups were conducted. Focus groups 1-3 centered on ranking 40 barriers to diabetes medication adherence (derived from REACH and the extant literature), whereas focus groups 4-5 centered on translation and cultural modifications of the original SMS text message content associated with each of the REACH barriers. Barriers were mapped onto information-motivation-behavioral constructs. We used descriptive statistics to summarize participant characteristics. Focus groups were audio-recorded, professionally transcribed, and analyzed with thematic content analysis using NVivo (Lumivero). Results: In total, 22 participants attended the focus groups. The mean (SD) age was 63.2 (11) years, 55% (n=10/22) were female, and the mean HbA1c level was 8.5%. All participants were born in Latin America or the Caribbean and spoke Spanish as their preferred language, and 54.5% (12/22) had completed middle-school education or less. Among the top 10 ranked barriers, 50% (n=5) corresponded to information, 20% (n=2) to social motivation, 20% (n=2) to behavioral skills, and 10% (n=1) to personal motivation. Personal motivation barriers (medication burden and fear of side effects) and behavioral skills (forgetting to take medication) emerged as important themes in the focus groups. Conclusions: A stakeholder-driven approach to intervention adaptation identified and prioritized relevant barriers to diabetes medication adherence among Latino adults with T2D and facilitated the adaptation of the REACH platform to a Spanish-speaking population.

Indexed as

Diabetes Mellitus, Type 2Hispanic or LatinoMedication AdherenceText MessagingAdultAgedFemaleFocus GroupsHumansMaleMiddle AgedQualitative Researchadherencediabetesdiabetes mellitusDMendocrinologyglycated hemoglobinHbA1cinterventionLatinoLatino adultsmedicationmedication adherencemessagingmultiphasenonadherencepopulationSpanish-speakingstakeholderstakeholder engagementT2DMtext messagingtype 1 diabetestype 2 diabetes

Identifiers

PMID40311126
PMCPMC12061353

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.