Evidence map›Paper›PMID 40311080›Full record

ArticleThe journal of physical chemistry. A2025

Parahydrogen-Hyperpolarized Propane-

Nuwandi M Ariyasingha, Clementinah Oladun, Anna Samoilenko, Md Raduanul H Chowdhury, Shiraz Nantogma, Zhongjie Shi, Kehuan Luo, Sidhartha Tan, Oleg G Salnikov, Alba Xhupi and 7 more

Abstract read
In one paragraph

Article in The journal of physical chemistry. A, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Machine learning-based prediction models for severeFrontiers in public health · 2026
    Pooled it
  3. Article
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  12. Post-pandemic resurgence and collapse ofFrontiers in public health · 2026
    Article
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  15. Article
  16. Article
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  18. Review
  19. Case Report: RefractoryFrontiers in pediatrics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Nuwandi M AriyasinghaDepartment of Chemistry, Integrative Biosciences (IBio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.
Clementinah OladunDepartment of Chemistry, Integrative Biosciences (IBio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.
Anna SamoilenkoDepartment of Chemistry, Integrative Biosciences (IBio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.
Md Raduanul H ChowdhuryDepartment of Chemistry, Integrative Biosciences (IBio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.
Shiraz NantogmaDepartment of Chemistry, Integrative Biosciences (IBio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.
Zhongjie ShiDepartment of Pediatrics, Wayne State University, Detroit, Michigan 48202, United States.
Kehuan LuoDepartment of Pediatrics, Wayne State University, Detroit, Michigan 48202, United States.
Sidhartha TanDepartment of Pediatrics, Wayne State University, Detroit, Michigan 48202, United States.
Oleg G SalnikovInternational Tomography Center SB RAS, 3A Institutskaya St., Novosibirsk 630090, Russia.ORCID 0000-0003-2266-7335
Alba XhupiDepartment of Chemistry, Integrative Biosciences (IBio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.
Majd SuleimanDepartment of Chemistry, Integrative Biosciences (IBio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.
Yuri A ChekmenevXeUS Technologies LTD., Nicosia 2312, Cyprus.
Larisa M KovtunovaInternational Tomography Center SB RAS, 3A Institutskaya St., Novosibirsk 630090, Russia.
Igor V KoptyugInternational Tomography Center SB RAS, 3A Institutskaya St., Novosibirsk 630090, Russia.ORCID 0000-0003-3480-7649
Juri G GelovaniDepartment of Chemistry, Integrative Biosciences (IBio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.
Boyd M GoodsonSchool of Chemical and Biomolecular Sciences, Southern Illinois University, Carbondale, Illinois 62901, United States.ORCID 0000-0001-6079-5077
Eduard Y ChekmenevDepartment of Chemistry, Integrative Biosciences (IBio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.ORCID 0000-0002-8745-8801

Funding

Probing Role of Tetrahydrobiopterin in Cerebral Palsy by Using Transgenic RabbitsR01NS117146 · NINDS · WAYNE STATE UNIVERSITY · PI TAN, SIDHARTHA, VASQUEZ VIVAR, JEANNETTE M. · 2021 to 2025
$3.1M
Neuroprotection by nNOS inhibitors in perinatal hypoxia-ischemiaR01NS114972 · NINDS · WAYNE STATE UNIVERSITY · PI TAN, SIDHARTHA · 2020 to 2024
$3.1M
Ferroptosis in knock-in sepiapterin reductase mutation rabbitsR01NS130258 · NINDS · WAYNE STATE UNIVERSITY · PI SIDHARTHA TAN, JEANNETTE M. VASQUEZ VIVAR · 2023 to 2026
$2.4M
Next-generation Lasers for Enabling Ultrafast Functional Pulmonary MRIR21HL168430 · NHLBI · WAYNE STATE UNIVERSITY · PI CHEKMENEV, EDUARD · 2024 to 2025
$379k
Next-generation ultrafast functional 3D pulmonary imagingF32HL160108 · NHLBI · WAYNE STATE UNIVERSITY · PI ARIYASINGHA U W, NUWANDI M · 2021 to 2023
$210k
NHLBI NIH HHS F32 HL160108NHLBI NIH HHS R21 HL168430NINDS NIH HHS R01 NS114972NINDS NIH HHS R01 NS117146NINDS NIH HHS R01 NS130258
6 · The paper itself

Abstract

Hyperpolarized (HP) MRI provides enhanced signals over conventional MRI due to the increase in nuclear spin polarization by orders of magnitude compared to thermal polarization. Therefore, HP MRI can be successfully utilized toward imaging of low-density gases in void spaces, such as human lungs. Specifically, in clinical pulmonary imaging, HP MRI employs a gaseous contrast agent that fills the lungs during inhalation under physiologically relevant conditions prior to imaging. FDA-approved HP

Indexed as

Contrast MediaHydrogenMagnetic Resonance ImagingPropaneGasesHumansPilot ProjectsXenon IsotopesContrast MediaGasesHydrogenPropaneXenon Isotopes

Identifiers

PMID40311080
PMCPMC12633766

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.