Evidence map›Paper›PMID 40310973›Full record

ArticleJournal of the American Chemical Society2025

Discrete Brush Polymers Enhance

Nduka D Ogbonna, Parikshit Guragain, Venkatesh Mayandi, Cyrus Sadrinia, Raman Danrad, Seetharama Jois, Jimmy Lawrence

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Structural Dispersity as a Determinant of Li-Ion Transport in Ethylene-Oxide-Based Graft Polymer Electrolytes.Chemistry of materials : a publication of the American Chemical Society · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nduka D OgbonnaDepartment of Chemical Engineering, Louisiana State University, Baton Rouge, Louisiana 70803, United States.
Parikshit GuragainDepartment of Chemical Engineering, Louisiana State University, Baton Rouge, Louisiana 70803, United States.
Venkatesh MayandiDepartment of Pathological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana 70803, United States.
Cyrus SadriniaDepartment of Radiology, School of Medicine, Louisiana State University Health, New Orleans, Louisiana 70112, United States.
Raman DanradDepartment of Radiology, School of Medicine, Louisiana State University Health, New Orleans, Louisiana 70112, United States.
Seetharama JoisDepartment of Pathological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana 70803, United States.ORCID 0000-0002-6936-772X
Jimmy LawrenceDepartment of Chemical Engineering, Louisiana State University, Baton Rouge, Louisiana 70803, United States.ORCID 0000-0003-4455-6177

Funding

Molecular mechanism of EGFRs protein-protein interaction inhibition by a grafted peptide in NSCLCR01CA255176 · NCI · UNIVERSITY OF LOUISIANA AT MONROE · PI BILLADEAU, DANIEL D, JOIS, SEETHARAMA D · 2021 to 2025
$1.7M
Discrete Polymer-based, Metal-free MRI Contrast AgentsR35GM151217 · NIGMS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI Jimmy Lawrence · 2023 to 2026
$1.5M
NCI NIH HHS R01 CA255176NIGMS NIH HHS R35 GM151217
6 · The paper itself

Abstract

The development of metal-free magnetic resonance imaging (MRI) agents demands precise control over molecular architecture to achieve optimal performance. Current fluorine-based contrast agents rely on maximizing fluorine content (>20 wt %) for sensitivity, requiring extensive solubilizing groups that lead to signal-diminishing aggregation. Here we show that discrete brush polymers (

Identifiers

PMID40310973
PMCPMC12082627

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.