Evidence map›Paper›PMID 40310935›Full record

ReviewInternational forum of allergy & rhinology2025

Allergic Fungal Rhinosinusitis Diagnosis, Management, Associated Conditions, Pathophysiology, and Future Directions: Summary of a Multidisciplinary Workshop.

Lauren T Roland, Cecelia Damask, Amber U Luong, Antoine Azar, Charles S Ebert, Thomas Edwards, Katherine N Cahill, Do-Yeon Cho, David Corry, Tara L Croston and 17 more

Abstract readReview
In one paragraph

Review in International forum of allergy & rhinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Lauren T RolandDepartment of Otolaryngology, Washington University in St Louis, St Louis, Missouri, USA.ORCID 0000-0003-2036-7611
Cecelia DamaskOrlando Ear, Nose, Throat, & Allergy, Lake Mary, Florida, USA.
Amber U LuongDepartment of Otorhinolaryngology, McGovern Medical School of the University of Texas Health Science Center at Houston, Houston, Texas, USA.ORCID 0000-0001-6078-8010
Antoine AzarDepartment of Medicine, Division of Allergy and Clinical Immunology, Johns Hopkins University, Baltimore, Maryland, USA.
Charles S EbertDepartment of Otolaryngology, University of North Carolina, Chapel Hill, North Carolina, USA.
Thomas EdwardsDepartment of Otolaryngology, Emory University, Atlanta, Georgia, USA.ORCID 0000-0002-6290-9506
Katherine N CahillDepartment of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Do-Yeon ChoDepartment of Otolaryngology, University of Alabama, Birmingham, Alabama, USA.ORCID 0000-0002-5173-8959
David CorryDepartment of Medicine, Baylor College of Medicine, Houston, Texas, USA.
Tara L CrostonHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia, USA.
Alexandra F FreemanPrimary Immune Deficiency Clinic, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, Maryland, USA.
Amin JaverSt Paul's Sinus Centre, Division of Otolaryngology, University of British Columbia, Canada.ORCID 0000-0001-9427-1853
Paneez KhouryEosinophil Clinical Research Unit, National Institute of Allergy and Infectious Disease, Baltimore, Maryland, USA.
Jean KimDepartment of Otolaryngology, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0001-7895-7193
Michael KovalDepartment of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0002-5422-5614
Edward D McCoulDepartment of Otorhinolaryngology, Ochsner Health, New Orleans, Louisiana, USA.
James W MimsDepartment of Otolaryngology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
Anju PetersDepartment of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0003-0745-2379
Jay F PiccirilloDepartment of Otolaryngology, Washington University in St Louis, St Louis, Missouri, USA.
Richard P RamonellDepartment of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-2385-0636
Amali SamarasingheDepartment of Medicine, University of Wisconsin Madison, Madison, Wisconsin, USA.
Robert P SchleimerDepartment of Medicine, Northwestern University, Chicago, Illinois, USA.
Prestina Smith-DavidsonDivision of Intramural Research, National Institute of Deafness and Other Communication Disorders, NIH, Bethesda, Maryland, USA.
Andrej SpecDepartment of Medicine, Washington University in St Louis, St Louis, Missouri, USA.
Michael E WechslerDepartment of Medicine, National Jewish Health, Denver, Colorado, USA.
Sarah K WiseDepartment of Otolaryngology, Emory University, Atlanta, Georgia, USA.
Joshua M LevyDivision of Intramural Research, National Institute of Deafness and Other Communication Disorders, NIH, Bethesda, Maryland, USA.ORCID 0000-0001-5907-3421

Funding

Washington University Institute of Clinical and Translational Sciences (KL2) KL2TR002346 · NCATS · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 2017 to 2026
$14.0M
Sinonasal and Olfaction ProgramZIADC000098 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI LEVY, JOSHUA · 2024 to 2025
$2.5M
Regulation of epithelial function using targeted nanowiresR01HL158979 · NHLBI · EMORY UNIVERSITY · PI DESAI, TEJAL A., KOVAL, MICHAEL H. · 2022 to 2025
$2.5M
American Academy of Otolaryngic Allergy (AAOA)American Rhinologic SocietyIntramural NIH HHS ZIA DC000098NCATS NIH HHS KL2 TR002346NHLBI NIH HHS R01 HL158979NIDCD Division of Intramural Research DC000098-02
6 · The paper itself

Abstract

Allergic fungal rhinosinusitis (AFRS) is a unique endotype of chronic rhinosinusitis with nasal polyps (CRSwNP). Despite high recurrence rates and often more severe presenting signs compared with other subtypes of CRSwNP, research dedicated to AFRS has been lacking. Diagnostic criteria are outdated, the mechanistic relationship of AFRS to other associated diseases is unclear, and the pathophysiology of disease and risk factors for recurrence have not been well studied. In December 2023, a multidisciplinary group of rhinologists, otolaryngologists, pulmonologists, allergists, immunologists, scientists, and infectious disease experts met at the National Institute of Health to discuss unmet needs for future AFRS research and care, including patient management, diagnostic criteria, severity, pathophysiology, and related conditions. A summary of these clinical and associated research discussions is included below.

Indexed as

MycosesRhinitis, AllergicSinusitisAllergic Fungal SinusitisChronic DiseaseHumansNasal Polypsallergic fungal sinusitisallergic sinusitischronic rhinosinusitisfungal sinusitisinvasive fungal sinusitisnasal polyps

Identifiers

PMID40310935
PMCPMC12645459

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.