Evidence map›Paper›PMID 40310728›Full record

ArticleOrthopaedic surgery2025

Clinical Application of 3D-Printed Custom Hemipelvic Prostheses With Negative Poisson's Ratio Porous Structures in Reconstruction After Resection of Pelvic Malignant Tumors.

Xin Hu, Chuang Li, Xiaodi Tang, Yitian Wang, Yi Luo, Yong Zhou, Chongqi Tu, Xiao Yang, Li Min

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Article in Orthopaedic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Xin HuDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Chuang LiOperating Room, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu, China.
Xiaodi TangDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Yitian WangDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Yi LuoDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Yong ZhouDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Chongqi TuDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0001-5273-7256
Xiao YangNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, China.
Li MinDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0002-1751-5479

Funding

National Key Research and Development Program of China 2023YFB3813002National Key Research and Development Program of China 2023YFE0126900National Science and Technology Major Project 2024ZD0525806Sichuan Science and Technology Agency 2022NSFSC0845
6 · The paper itself

Abstract

objectivesPelvic bone tumor resection and reconstruction present significant challenges due to complex anatomy and weight-bearing demands. 3D-printed hemipelvic prostheses, incorporating customized osteotomy guides and porous structures, offer a promising solution for enhancing osseointegration. This study evaluates the long-term outcomes of 3D-printed custom hemipelvic reconstruction with a focus on the integration of auxetic biomaterials with a negative Poisson's ratio to optimize mechanical properties.

methodsA retrospective analysis was conducted on 12 patients with primary pelvic malignancies who underwent reconstruction using 3D-printed hemipelvic prostheses between January 2018 and May 2023. Follow-up duration was 48 months (range, 29-64 months) Oncological, functional, surgical, pain control, and radiographic outcomes were assessed.

resultsAt the latest follow-up, 8 patients (66.7%) were disease-free, 3 (25%) had disease progression, and 1 (8.3%) died from metastatic complications. Functional outcomes improved significantly, with the MSTS-93 score increasing from 15 (range, 12-17) to 26 (range, 21-29). Pain scores decreased from 5 (range, 4-7) to 1 (range, 0-2). The median surgical duration was 270 min (range, 150-560 min), with intraoperative blood loss averaging 3200 mL (range, 1900-6300 mL). Complications included poor wound healing in 2 patients (16.7%), managed with VAC drainage. No mechanical failures, loosening, or fractures occurred. Accurate osteotomy, prosthesis implantation, and screw fixation were achieved. Successful osseointegration was observed in all cases, with no signs of bone absorption or osteolysis.

conclusions3D-printed custom hemipelvic prostheses with auxetic biomaterials offer an effective solution for pelvic reconstruction, providing promising oncological, functional, and radiographic outcomes. These findings support the use of 3D printing in complex pelvic defect reconstruction, optimizing both osteointegration and mechanical strength.

Indexed as

Bone NeoplasmsPelvic BonesPelvic NeoplasmsPlastic Surgery ProceduresPrinting, Three-DimensionalProstheses and ImplantsProsthesis DesignAdultAgedFemaleHumansMaleMiddle AgedPorosityRetrospective StudiesYoung Adult3D‐printedhemipelvectomyosteosarcomaprostheses

Identifiers

PMID40310728
PMCPMC12146138

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.