Evidence map›Paper›PMID 40310585›Full record

ArticleDiscover oncology2025

TMCO1, as a potential biomarker of prognosis and immunotherapy response, regulates head and neck squamous cell carcinoma proliferation and migration.

Ting Li, Lu Chen, Guangkai Zhou, Yuhan Deng, Meng Zhou, Mingze Yan, Shuyan Dong, Kaixun Xing, Shan Yu, Hongjiang He

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ting Li *Department of Head and Neck Surgery, Harbin Medical University Cancer Hospital, No. 150 Haping Road, Nangang District, Harbin, 150081, Heilongjiang, China.
Lu Chen *Department of Pathology, Second Affiliated Hospital of Harbin Medical University, No. 246 XueFu Road, Harbin, 150086, Heilongjiang, China.
Guangkai ZhouDepartment of Head and Neck Surgery, Harbin Medical University Cancer Hospital, No. 150 Haping Road, Nangang District, Harbin, 150081, Heilongjiang, China.
Yuhan DengDepartment of Breast Surgery, Harbin Medical University Cancer Hospital, No. 150 Haping Road, Nangang District, Harbin, 150081, Heilongjiang, China.
Meng ZhouDepartment of Anesthesiology, Harbin Medical University Cancer Hospital, No. 150 Haping Road, Nangang District, Harbin, 150081, Heilongjiang, China.
Mingze YanDepartment of Head and Neck Surgery, Harbin Medical University Cancer Hospital, No. 150 Haping Road, Nangang District, Harbin, 150081, Heilongjiang, China.
Shuyan DongDepartment of Head and Neck Surgery, Harbin Medical University Cancer Hospital, No. 150 Haping Road, Nangang District, Harbin, 150081, Heilongjiang, China.
Kaixun XingDepartment of Head and Neck Surgery, Harbin Medical University Cancer Hospital, No. 150 Haping Road, Nangang District, Harbin, 150081, Heilongjiang, China.
Shan YuDepartment of Pathology, Second Affiliated Hospital of Harbin Medical University, No. 246 XueFu Road, Harbin, 150086, Heilongjiang, China. yushan@hrbmu.edu.cn.
Hongjiang HeDepartment of Head and Neck Surgery, Harbin Medical University Cancer Hospital, No. 150 Haping Road, Nangang District, Harbin, 150081, Heilongjiang, China. hehongjiang@ems.hrbmu.edu.cn.

Funding

China Primary Health Care Foundation 2022/2023-001Research Project of the Heilongjiang Province Health Commission No. 2019-057the Haiyan Scientific Research Fund of Harbin Medical University Cancer Hospital No. JJMS2021-16
6 · The paper itself

Abstract

Transmembrane and coiled-coil domains 1 (TMCO1), an endoplasmic reticulum transmembrane protein, actively regulates intracellular Ca

Indexed as

BiomarkerHNSCCImmunotherapyPrognosisTMCO1

Identifiers

PMID40310585
PMCPMC12045888

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.