ArticleVeterinary research communications2025
Effects of glutamine supplementation on the growth performance, antioxidant capacity, immunity and intestinal morphology of cold-stressed prestarter broiler chicks.
Article in Veterinary research communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Appropriate Rumen-Protected Glutamine Supplementation During Late Gestation in Ewes Promotes Lamb Growth and Improves Maternal and Neonatal Metabolic, Immune and Microbiota Functions.Animals : an open access journal from MDPI · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundCold stress has important effects on the growth and production of broiler chickens. Glutamine (Gln) is a conditionally essential amino acid that plays an important role in promoting intestinal development and enhancing immune function. The aim of this study was to investigate the effects of Gln supplementation on the growth performance and health of cold-stressed prestarter broiler chicks. METHODS AND
resultsA total of 375 1-day-old male SZ901 broilers were randomly divided into five groups (CON, CS, GLN1, GLN2, GLN3). Birds in the CON and CS groups were provided with normal drinking water, while the GLN1, GLN2 and GLN3 groups were provided with water supplemented with 0.4%, 0.8% and 1.2% Gln, respectively. At d7, birds in groups CS, GLN1, GLN2, and GLN3 were stressed at 12 ± 1 ℃ for 12 h. The results showed that cold stress significantly decreased the growth performance, serum antioxidant capacity and antibody concentrations, small intestine villus structure, and increased the gene expression of intestinal inflammatory factors of broiler chicks compared with the CON group (P < 0.05). Compared with the CS group, Gln supplementation exhibited increased growth performance, serum antioxidant capacity and antibody concentrations, gene expression levels of intestinal tight junction protein, villus height and villus height to crypt depth ratio (V/C) of small intestine, and decreased mRNA expression level of intestinal inflammatory factors (P < 0.05).
conclusionsGln supplementation ameliorated the impact of cold stress to a large extent as it promoted the development of the intestine and immune system and enhanced the antioxidant enzyme system in cold-stressed prestarter chicks.
Indexed as
Identifiers
40310539What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.