Evidence map›Paper›PMID 40310521›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Utilizing temporal imaging to enhance early diagnosis of eosinophilic otitis media in clinical practice.

Chenyu Chen, Hongjing Wu, Binjun Chen, Haojie Sun, Xiying Huang, Dongdong Ren

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Chenyu ChenENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Hongjing WuDepartment of Otorhinolaryngology, Head and Neck Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Binjun ChenENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Haojie SunENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Xiying HuangDepartment of Otorhinolaryngology, Head and Neck Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Dongdong RenENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China. dongdongren@fudan.edu.cn.

Funding

National Natural Science Foundation of China 81771017National Natural Science Foundation of China 81970880National Natural Science Foundation of China 82271166Natural Science Foundation of Shanghai 22ZR1410100
6 · The paper itself

Abstract

purposeThe diagnosis of eosinophilic otitis media (EOM) remains a major challenge. Current diagnostic methods rely primarily on accurate samples of middle ear tissue or secretions, which can be complex. In this study, we sought to explore the diagnostic value of mastoid pneumatization combined with other temporal radiological features for EOM.

methodsThis study included 28 patients with EOM and 32 patients with ordinary OM. All participants underwent the temporal bone HRCT, and middle ear status was assessed using four sections: mesotympanum, attic, antrum, and mastoid air cells. Quantification of negative temporal bone pressure using three-dimensional analysis of mastoid volume images.

resultsThe volumes of eosinophilic/non-eosinophilic mastoid air cells were approximately the same but were asymmetric. In contrast, in the normal OM group, there was a significant difference in the volume of mastoid air cells between the inflammatory and non-inflammatory sides. Statistically, the degree of opacification to the mesotympanum, attic, and mastoid air cells was more severe in patients with EOM than in patients with ordinary OM on the affected side. Furthermore, on the normal side, the opacification of the all four sites in the eosinophil group was basically worse than that in the control group.

conclusionEosinophilic individuals have been found to be specific to the mastoid air cell system and middle ear status and are important factors to consider. Therefore, the potential imaging information of HRCT can help otologists diagnose EOM earlier and provide timely and effective treatment.

Indexed as

EosinophiliaMastoidOtitis MediaTemporal BoneTomography, X-Ray ComputedAdolescentAdultAgedEarly DiagnosisEar, MiddleFemaleHumansImaging, Three-DimensionalMaleMiddle AgedYoung AdultAllergyDiagnosisEosinophilic otitis mediaHigh-resolution computed tomographyMastoid pneumatizationTemporal bone

Identifiers

PMID40310521

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