Evidence map›Paper›PMID 40310513›Full record

ArticleSports medicine (Auckland, N.Z.)2025

Associations of Collegiate Football Career and Incident Concussion with Players' Health: A Longitudinal Study from the CARE Consortium.

Katherine J Hunzinger, Jaclyn B Caccese, Connor A Law, Rachael M Wittmer, Thomas A Buckley, Steven P Broglio, Thomas W McAllister, Michael A McCrea, Paul F Pasquina, Andrea L C Schneider and 1 more

Abstract read
In one paragraph

Article in Sports medicine (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

11 authors.

Katherine J HunzingerDepartment of Exercise Science, Ronson Health and Applied Science Center, Thomas Jefferson University, 225E, 4201 Henry Ave., Philadelphia, PA, 19144, USA. Katherine.Hunzinger@Jefferson.edu.ORCID 0000-0002-4599-8543
Jaclyn B CacceseThe Ohio State University Chronic Brain Injury Program, The Ohio State University College of Medicine, Columbus, OH, USA.
Connor A LawDepartment of Neurology, University of Pennsylvania-Perelman School of Medicine, Philadelphia, PA, USA.
Rachael M WittmerSidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Thomas A BuckleyDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, DE, USA.
Steven P BroglioMichigan Concussion Center, University of Michigan, Ann Arbor, MI, USA.
Thomas W McAllisterDepartment of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA.
Michael A McCreaDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, USA.
Paul F PasquinaWalter Reed National Military Medical Center, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Andrea L C SchneiderDepartment of Neurology, University of Pennsylvania-Perelman School of Medicine, Philadelphia, PA, USA.
CARE Consortium Investigators

Funding

Combat Casualty Care Research Program W81XWH1420151
6 · The paper itself

Abstract

backgroundThe influence of repetitive head impacts on collegiate football players remains unclear as prior research is often limited to small samples or short-term studies focused on single seasons.

objectiveOur objective was to determine the associations between collegiate football career or incident concussion and changes in neurocognitive function, postural stability, and physical and psychological health.

methodsIn total, 574 football players enrolled in the Grand Alliance Concussion Assessment, Research and Education (CARE) Consortium (median age 18.0 years [interquartile range 18.0-19.0], 52% white race, 26% with incident concussion) completed baseline and exit evaluations (i.e., beginning and end of collegiate career) consisting of neurocognitive, postural stability, and physical/psychological health assessments, specifically, Immediate Post-Concussion Assessment and Cognitive Testing, Standardized Assessment of Concussion, Balance Error Scoring System, Sport Concussion Assessment Tool-5 (SCAT-5) Symptom checklist, and the Brief Symptom Inventory-18. Adjusted linear regression models incorporating inverse probability of attrition weighting were used to compare changes in scores between baseline and exit evaluations overall and by incident concussion status.

resultsOverall, athletes had small improvements in neurocognitive functioning and postural stability over time but had small increases in symptom severity. Both the incident concussion and no incident concussion groups improved similarly on neurocognitive and postural stability measures (all p > 0.05 for difference in change over time between incident concussion groups). Individuals with incident concussion reported fewer symptoms and lower symptom severity over time than did those without incident concussion (SCAT symptom count difference - 1.22; 95% confidence interval [CI] - 1.89 to - 0.54; SCAT symptom severity difference: - 2.46; 95% CI - 4.06 to - 0.86; Brief Symptom Inventory-18 somatization difference: - 0.55; 95% CI - 0.93 to - 0.17).

conclusionsOverall, collegiate football players demonstrated small, non-clinically meaningful improvements in neurocognitive function and postural stability. Moreover, athletes who experienced a concussion reported slight improvements in physical/psychological health symptoms over their collegiate careers.

Indexed as

Athletic InjuriesBrain ConcussionFootballAdolescentAthletesCognitionHumansLongitudinal StudiesMaleNeuropsychological TestsPostural BalanceUniversitiesYoung Adult

Identifiers

PMID40310513
PMCPMC12476394

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.