Evidence map›Paper›PMID 40310505›Full record

ArticleMetabolic brain disease2025

Metabolic dysregulation in amyotrophic lateral sclerosis: insights from

Priyanka Gautam, Rahul Yadav, Ranjeet Kumar Vishwakarma, Abhishek Pathak, Chandan Singh

Abstract read
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In one paragraph

Article in Metabolic brain disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Metabolomic analyses of amyotrophic lateral sclerosis, muscle cramps, and TJ-68 treatment.Metabolomics : Official journal of the Metabolomic Society · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Priyanka GautamDepartment of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, Uttar Pradesh, India.ORCID 0000-0002-4669-1527
Rahul YadavDepartment of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221005, Uttar Pradesh, India.ORCID 0009-0006-1402-2392
Ranjeet Kumar VishwakarmaDepartment of Physiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, Uttar Pradesh, India.ORCID 0009-0001-8508-2740
Abhishek PathakDepartment of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, Uttar Pradesh, India. abhishekpathakaiims@gmail.com.ORCID 0000-0002-5975-1699
Chandan SinghDepartment of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221005, Uttar Pradesh, India. chandansingh@bhu.ac.in.ORCID 0000-0001-8006-1329

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disorder characterized by motor neuron loss, leading to severe physical impairment and mortality. Despite available treatments like Riluzole and Edaravone, their limited efficacy highlights the need for improved understanding of ALS pathology. This study has explored metabolic alterations in North Indian ALS patients using

Indexed as

Amyotrophic Lateral SclerosisMetabolomicsAdultAgedBiomarkersCase-Control StudiesFemaleHumansIndiaMagnetic Resonance SpectroscopyMaleMiddle AgedPilot ProjectsProton Magnetic Resonance SpectroscopyTertiary Care CentersBiomarkersAmyotrophic lateral sclerosisBiomarkerMetabolic pathwayNuclear magnetic resonanceSerumUntargeted metabolomics

Identifiers

PMID40310505

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.