Evidence map›Paper›PMID 40310455›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Detecting DNA translocation through a nanopore using a van der Waals heterojunction diode.

Sihan Chen, Siyuan Huang, Jangyup Son, Edmund Han, Kenji Watanabe, Takashi Taniguchi, Pinshane Y Huang, William P King, Arend M van der Zande, Rashid Bashir

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Detecting DNA translocation through a nanopore using a van der Waals heterojunction diode.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Sihan ChenHolonyak Micro and Nanotechnology Laboratory, The Grainger College of Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0003-1216-6422
Siyuan HuangDepartment of Mechanical Science and Engineering, The Grainger College of Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801.
Jangyup SonDepartment of Mechanical Science and Engineering, The Grainger College of Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801.
Edmund HanDepartment of Materials Science and Engineering, The Grainger College of Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0002-1910-9052
Kenji WatanabeResearch Center for Electronic and Optical Materials, National Institute for Materials Science, Tsukuba 305-0044, Ibaraki, Japan.
Takashi TaniguchiResearch Center for Materials Nanoarchitectonics, National Institute for Materials Science, Tsukuba 305-0044, Ibaraki, Japan.
Pinshane Y HuangDepartment of Materials Science and Engineering, The Grainger College of Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0002-1095-1833
William P KingHolonyak Micro and Nanotechnology Laboratory, The Grainger College of Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0001-8606-1290
Arend M van der ZandeHolonyak Micro and Nanotechnology Laboratory, The Grainger College of Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0001-5104-9646
Rashid BashirHolonyak Micro and Nanotechnology Laboratory, The Grainger College of Engineering, University of Illinois Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0002-7225-9180

Funding

Atomically-thin diode integrated into a nanopore DNA SensorR21HG010701 · NHGRI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BASHIR, RASHID, VAN DER ZANDE, AREND · 2019 to 2020
$398k
HHS | NIH | National Human Genome Research Institute (NHGRI) R21HG010701MEXT | Japan Society for the Promotion of Science (JSPS) 21H05233MEXT | Japan Society for the Promotion of Science (JSPS) 23H02052NHGRI NIH HHS R21 HG010701NSF | MPS | Division of Materials Research (DMR) 2309037Wellcome Trust 089401
6 · The paper itself

Abstract

A long-unrealized goal in solid-state nanopore sensing is to achieve out-of-plane electrical sensing and control of DNA during translocation, which is a prerequisite for base-by-base ratcheting that enables DNA sequencing in biological nanopores. Two-dimensional (2D) heterostructures, with their capability to construct out-of-plane electronics with atomic layer precision, are ideal yet unexplored candidates for use as electrical sensing membranes. Here, we demonstrate a nanopore architecture using a vertical 2D heterojunction diode consisting of p-type WSe

Indexed as

DNANanoporesDisulfidesMolybdenumSemiconductorsStatic ElectricityDisulfidesDNAMolybdenummolybdenum disulfideDNAion transportnanoporesingle moleculevan der Waals heterojunction

Identifiers

PMID40310455
PMCPMC12067215

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.