ArticleChildren (Basel, Switzerland)2025
The Clinical Value of Capillary Blood Cartridge-Based Testing in Neonatal Jitteriness: A Re-Evaluation of the Diagnostic Approach.
Article in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThis study assessed the utility of capillary blood cartridge-based analysis in evaluating neonatal jitteriness (NJ).
methodsIn this retrospective study, we compared outcomes between neonates (37-41 weeks of gestation) diagnosed with neonatal jitteriness (NJ) within the first 72 h of life and a control group of healthy neonates (GA 37-41 weeks) with an uneventful perinatal course and no signs of jitteriness.
resultsEach group included 101 neonates. Jittery neonates had a higher proportion of males (70.3% vs. 50.5%,
conclusionsPoint-of-care glucose testing using a bedside glucometer may be sufficient for the evaluation of neonatal jitteriness, as capillary blood cartridge-based testing did not offer an additional diagnostic value. WHAT IS KNOWN: NJ is often viewed as a self-resolving benign phenomenon; however, in certain cases, it can be an indicator of an underlying pathology. There is substantial evidence linking the maternal use of SSRIs or SNRIs during pregnancy with the occurrence of NJ in newborns as well as an association between hypoglycemia and NJ. WHAT IS NEW: This study is the first to evaluate the clinical utility of systematic capillary blood cartridge-based testing in jittery neonates using a relatively large cohort. Male neonates were disproportionately represented among cases of NJ. Healthy neonates with jitteriness had normal electrolytes, with hypoglycemia as the only concern. A glucometer test may suffice for evaluation, but those who are small for their gestational age or have initial hypoglycemia require a routine follow-up due to a higher risk of NICU admission.
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