ReviewChildren (Basel, Switzerland)2025
Salivary Markers as Potential Stress Descriptors for Pediatric Dental Patients: A Literature Review.
Review in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Effects of different dental local anesthesia techniques on salivary cortisol and secretory immunoglobulin a in pediatric patients: a randomized controlled clinical study.Clinical oral investigations · 2026Trial
- Salivary opiorphin as a potential non-invasive biomarker for dental anxiety.BMC oral health · 2026Article
- Non-Pharmacological Interventions for Managing Preoperative Anxiety in the Context of Odontectomy: A Systematic Review.Dentistry journal · 2026Review
- Review
- Sleep and circadian disruption reshape immune homeostasis in oral tissues: mechanistic roles of melatonin and cortisol in periodontal disease and xerostomia.Frontiers in immunology · 2026Review
- Article
- A Cross-Sectional Study of Salivary Cortisol, Alpha Amylase, and Measures of Psychological Distress in Children Undergoing Dental Procedures.Children (Basel, Switzerland) · 2025Article
- Effect of Midazolam Premedication on Salivary Cortisol Levels in Pediatric Patients with Negative Frankl Behavior: A Pilot Study.Children (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dental fear and anxiety are frequently identified as major contributing factors to non-compliance, uncooperativeness, and difficulties during dental procedures in pediatric patients. These issues can lead to avoidance of dental treatment, resulting in long-term negative consequences for oral health and overall well-being. The assessment and quantification of psychological functioning (i.e., dental fear, anxiety, and self-perceived stress) has traditionally relied on self-reported questionnaires validated for the pediatric population. While this approach is cost-effective and non-invasive, it relies on subjective self-reported data, oftentimes influenced by parental or guardian interaction, especially in young children. Salivary diagnostics has recently emerged as an objective method for the procurement of biological molecules that serve as biomarkers for a variety of oral and systemic conditions. This literature review aims to comprehensively summarize the available literature on the correlation between psychological and salivary physiological measurements assessing dental fear, dental anxiety, and self-perceived stress in pediatric dental patients, highlighting the advantages and disadvantages of each method of assessment. Four databases (PubMed
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.