Evidence map›Paper›PMID 40309827›Full record

ArticleBrain sciences2025

Genetic Screening for Hereditary Transthyretin Amyloidosis in the Population of Cammarata and San Giovanni Gemini Through Red Flags and Registry Archives.

Vincenzo Di Stefano, Christian Messina, Antonia Pignolo, Fiore Pecoraro, Ivana Cutrò, Paolo Alonge, Nicasio Rini, Umberto Quartetti, Vito Lo Bue, Eugenia Borgione and 1 more

Abstract read
In one paragraph

Article in Brain sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The role of "red flags" in the diagnostic work-up of hereditary transthyretin amyloidosis: a study using a machine-learning approach.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Vincenzo Di StefanoDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo, 90129 Palermo, Italy.ORCID 0000-0001-9805-1655
Christian MessinaDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo, 90129 Palermo, Italy.ORCID 0000-0003-3027-7863
Antonia PignoloDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo, 90129 Palermo, Italy.ORCID 0000-0002-8883-5701
Fiore PecoraroDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo, 90129 Palermo, Italy.
Ivana CutròDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo, 90129 Palermo, Italy.
Paolo AlongeDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo, 90129 Palermo, Italy.ORCID 0009-0001-3627-8974
Nicasio RiniDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo, 90129 Palermo, Italy.
Umberto QuartettiDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo, 90129 Palermo, Italy.
Vito Lo BueDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo, 90129 Palermo, Italy.
Eugenia BorgioneOasi Research Institute-IRCCS, Via Conte Ruggero 73, 94018 Troina, Italy.ORCID 0000-0001-5458-7415
Filippo BrighinaDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (BiND), University of Palermo, 90129 Palermo, Italy.ORCID 0000-0001-5875-3126

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ATTRv-PNgeneticshereditary transthyretin amyloidosisneuromuscularneuropathyneurophysiologyscreeningTTR amyloid

Identifiers

PMID40309827
PMCPMC12025942

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.