Evidence map›Paper›PMID 40309812›Full record

ArticleOrthopaedic surgery2025

Clinical Outcomes of N-HA/pa66 and Titanium Mesh in the Treatment of Lower Cervical Spine Fractures and Dislocations During an 8-Year Follow-Up Period.

Chen Wang, Yujie Hu, Ying Liu, Jiangbin Tang, Xi Yang

Abstract read
In one paragraph

Article in Orthopaedic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [Eccentric kyphotic distraction reduction technique for treatment of lower cervical dislocation with locked facet joints].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chen WangDepartment of Orthopaedic Surgery, West China Xiamen Hospital, Sichuan University, Xiamen, China.ORCID https://orcid.org/0009-0006-3260-6244
Yujie HuState Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Ying LiuDepartment of Orthopaedic Surgery, West China Xiamen Hospital, Sichuan University, Xiamen, China.
Jiangbin TangDepartment of Orthopaedic Surgery, West China Xiamen Hospital, Sichuan University, Xiamen, China.
Xi YangDepartment of Orthopaedic Surgery, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0001-7925-3323

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveStudies evaluating the long-term outcomes of the nano-hydroxyapatite/polyamide 66 cages (n-HA/PA66) in treating lower cervical spine fractures have not been reported. The objective is to compare the long-term clinical and radiographic outcomes of titanium mesh cage (TMC) and-HA/PA66 for anterior cervical corpectomy and fusion (ACCF) in the treatment of lower cervical spine fractures and dislocations.

methodThis retrospective analysis included 223 patients treated at our hospital between January 2010 and January 2016 who had undergone single-level anterior corpectomy for lower cervical spine fractures and dislocations (with a minimum follow-up of 8 years) using either a TMC (n = 130) or an n-HA/PA66 cage (n = 93). The radiographic parameters, including segmental alignment (SA), cage subsidence, plate-to-disc distance, cervical lordosis (CL), intervertebral height, and fusion status, along with clinical metrics such as Japanese Orthopedic Association (JOA) scores and visual analog scale (VAS) assessments, were systematically analyzed at preoperative, postoperative, and final follow-up intervals for the patients involved in the study. The Chi-Square (χ

resultThe mean follow-up durations for the TMC group and n-HA/PA66 group were9.81 ± 2.21 and 9.43 ± 0.92 years, respectively. Moreover, final fusion rates were not significantly different between the n-HA/PA66 group and the TMC group (97.8% and 96.9%, respectively). The final cage subsidence was significantly lower in the n-HA/PA66 group (1.56 ± 0.88 mm, with 17.6% subsidence of > 3 mm) than in the TMC group (2.70 ± 2.02 mm, with 36.9% subsidence) (p < 0.01). Furthermore, CL, SA, plate-to-disc distance, JOA scores, and VAS scores were not significantly different between the two groups (all p > 0.05).

conclusionWithin 8 years following single level ACCF surgery, the n-HA/PA66 cage may be better than TMC in anterior cervical construction for treating lower cervical fractures and dislocations.

Indexed as

Cervical VertebraeFracture Fixation, InternalJoint DislocationsSpinal FracturesSpinal FusionSurgical MeshAdultAgedDurapatiteFemaleFollow-Up StudiesHumansMaleMiddle AgedNylonsRetrospective StudiesDurapatiteNylonsTitaniumanterior cervical corpectomy and fusionlower cervical spine fracture and dislocationnano‐hydroxyapatite/Polyamide66 cagetitanium mesh cage

Identifiers

PMID40309812
PMCPMC12146112

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.