Evidence map›Paper›PMID 40309725›Full record

ArticleFrontiers in medicine2025

Variations in capillary and serum lactates levels based on different etiologies of septic patients in the emergency department.

Matteo Guarino, Benedetta Perna, Giacomo Maroncelli, Paolo Baldin, Chiara Donati, Francesco Luppi, Alice Eleonora Cesaro, Chiara Pesci, Anna Costanzini, Martina Maritati and 4 more

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Matteo GuarinoDepartment of Translational Medicine, St. Anna University Hospital of Ferrara, University of Ferrara, Ferrara, Italy.
Benedetta PernaDepartment of Translational Medicine, St. Anna University Hospital of Ferrara, University of Ferrara, Ferrara, Italy.
Giacomo MaroncelliDepartment of Translational Medicine, St. Anna University Hospital of Ferrara, University of Ferrara, Ferrara, Italy.
Paolo BaldinDepartment of Translational Medicine, St. Anna University Hospital of Ferrara, University of Ferrara, Ferrara, Italy.
Chiara DonatiDepartment of Translational Medicine, St. Anna University Hospital of Ferrara, University of Ferrara, Ferrara, Italy.
Francesco LuppiDepartment of Translational Medicine, St. Anna University Hospital of Ferrara, University of Ferrara, Ferrara, Italy.
Alice Eleonora CesaroDepartment of Translational Medicine, St. Anna University Hospital of Ferrara, University of Ferrara, Ferrara, Italy.
Chiara PesciDepartment of Emergency, St. Anna University Hospital of Ferrara, Ferrara, Italy.
Anna CostanziniDepartment of Translational Medicine, St. Anna University Hospital of Ferrara, University of Ferrara, Ferrara, Italy.
Martina MaritatiInfectious Diseases Unit, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
Paolo ClavenzaniDepartment of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.
Carlo ContiniInfectious Diseases Unit, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
Roberto De GiorgioDepartment of Translational Medicine, St. Anna University Hospital of Ferrara, University of Ferrara, Ferrara, Italy.
Michele Domenico SpampinatoDepartment of Translational Medicine, St. Anna University Hospital of Ferrara, University of Ferrara, Ferrara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Sepsis is a life-threating and time-depending condition. This study examined the association between sepsis etiology and variations in capillary and serum lactate levels, neutrophil-to-lymphocyte ratio, and diastolic shock index in emergency department patients. Methods: This study, conducted between 2021 and 2022 at the Emergency Department of Ferrara, included the following criteria: (i) clinical suspect of infectious disease; (ii) qSOFA ≥2; (iii) age ≥18 years; (iv) signed informed consent. Etiologies were: (i) negative cultures (NC); (ii) Gram positive (GP); (iii) Gram negative (GN); (iv) fungal infections (FI). Results: Among the 200 included patients, 104 (52.0%) had NC, 36 (18.0%) GP, 53 (26.5%) GN and 7 (3.5%) FI. CLs ( Conclusion: All parameters differed according to sepsis etiology, thus improving early prediction of sepsis etiology and its pharmacological management.

Indexed as

diastolic shock indexetiologylactatesneutrophil-to-lymphocyte ratiosepsisseptic shock

Identifiers

PMID40309725
PMCPMC12040905

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