Evidence map›Paper›PMID 40309714›Full record

ArticleJTCVS open2025

Presentation, management, and clinical outcomes of acute type A dissection: Does sex matter?

Frederike Meccanici, Carlijn G E Thijssen, Arjen L Gökalp, Marie H E J van Wijngaarden, Mark F A Bierhuizen, Guy F Custers, Jort Evers, Jolien A de Veld, Maximiliaan L Notenboom, Guillaume S C Geuzebroek and 8 more

Abstract read
In one paragraph

Article in JTCVS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Frederike MeccaniciDepartment of Congenital Cardiology, Erasmus MC, Rotterdam, The Netherlands.
Carlijn G E ThijssenDepartment of Congenital Cardiology, Erasmus MC, Rotterdam, The Netherlands.
Arjen L GökalpDepartment of Cardiothoracic Surgery, Erasmus MC, Rotterdam, The Netherlands.
Marie H E J van WijngaardenDepartment of Cardiothoracic Surgery, Erasmus MC, Rotterdam, The Netherlands.
Mark F A BierhuizenDepartment of Cardiothoracic Surgery, Erasmus MC, Rotterdam, The Netherlands.
Guy F CustersDepartment of Cardiothoracic Surgery, Erasmus MC, Rotterdam, The Netherlands.
Jort EversDepartment of Cardiothoracic Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
Jolien A de VeldDepartment of Congenital Cardiology, Erasmus MC, Rotterdam, The Netherlands.
Maximiliaan L NotenboomDepartment of Cardiothoracic Surgery, Erasmus MC, Rotterdam, The Netherlands.
Guillaume S C GeuzebroekDepartment of Cardiothoracic Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
Joost F J Ter WoorstDepartment of Cardiothoracic Surgery, Catharina Ziekenhuis, Eindhoven, The Netherlands.
Jelena SjatskigDepartment of Cardiothoracic Surgery, Erasmus MC, Rotterdam, The Netherlands.
Robin H HeijmenDepartment of Cardiothoracic Surgery, St Antonius Ziekenhuis, Nieuwegein, The Netherlands.
Mostafa M MokhlesDepartment of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands.
Roland R J van KimmenadeDepartment of Congenital Cardiology, Erasmus MC, Rotterdam, The Netherlands.
Jos A BekkersDepartment of Cardiothoracic Surgery, Erasmus MC, Rotterdam, The Netherlands.
Johanna J M TakkenbergDepartment of Cardiothoracic Surgery, Erasmus MC, Rotterdam, The Netherlands.
Jolien W Roos-HesselinkDepartment of Congenital Cardiology, Erasmus MC, Rotterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Male-female differences in clinical presentation, management, and outcomes of acute type A aortic dissection (AD-A) have been reported; however, robust data are scarce. This study examined those differences. Methods: Consecutive adults diagnosed with AD-A between 2007 and 2017 in 4 referral centers were included retrospectively. Baseline data, operative characteristics, and mortality and morbidity during follow-up were collected using patient files, questionnaires, and referral information. Results: The study included 889 patients (37.5% female). Females were significantly older at presentation (median, 67.0 [interquartile range [IQR], 59.0-75.0] years vs 61.0 [IQR, 53.0-69.0] years; Conclusions: These findings highlight a distinct clinical profile at presentation with AD-A between males and females, while treatment approach and short-term mortality were comparable. The relatively poor long-term survival in females and male-/female-specific risk stratification warrant further investigation.

Indexed as

clinical presentationgenderoutcomessexStanford type A aortic dissectionsurvival

Identifiers

PMID40309714
PMCPMC12039451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.