Evidence map›Paper›PMID 40309708›Full record

ArticleJTCVS open2025

Are early outcomes of reoperative aortic root surgery impacted by previous root procedure and indication for reintervention?

Haytham Elgharably, Haley Jenkins, Davut Cekmecelioglu, Kamal S Ayyat, Ahmed K Awad, Patrick R Vargo, Shinya Unai, Eric E Roselli, Lars G Svensson, Gosta B Pettersson

Abstract read
In one paragraph

Article in JTCVS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Haytham ElgharablyDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
Haley JenkinsDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
Davut CekmeceliogluDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
Kamal S AyyatDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
Ahmed K AwadDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
Patrick R VargoDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
Shinya UnaiDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
Eric E RoselliDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
Lars G SvenssonDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
Gosta B PetterssonDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Reoperative aortic root surgery after a previous root procedure is technically demanding, which can impact outcomes. Herein, we examined the impact of previous root procedure and operative indication on early outcomes. Methods: From January 2010 to December 2022, 632 patients underwent reoperative aortic root surgery after previous root procedure (true redo root) at our institution. Baseline characteristics, operative details, and in-hospital complications were compared between groups on the basis of type of previous root prosthesis and infective endocarditis indication. Results: In the whole cohort, the operative mortality was 2.2% and estimated survival was 93%, 80%, and 67% at 1, 5, and 10 years, respectively. Operative mortality was similar between previous homograft, Bentall, Freestyle, valve-sparing root reimplantation, and Ross (2%, 4%, 0%, 4%, and 0%, respectively, Conclusions: At experienced centers, aortic root reoperation (true redo root) can be performed with low operative mortality. Explant of prosthetic graft material and endocarditis are associated with more complicated postoperative course, without significantly increased operative mortality.

Indexed as

aortic root replacementcardiac reoperationhomograftinfective endocarditis

Identifiers

PMID40309708
PMCPMC12039431

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.