Evidence map›Paper›PMID 40309695›Full record

ArticleJTCVS open2025

Role of a multidisciplinary team approach in the management of chronic thromboembolic pulmonary hypertension.

Benjamin Yang, Anthony Zaki, Nicholas Oh, Juan Umana-Pizano, Ihab Haddadin, Alice Goyanes, Nicholas Smedira, Haytham Elgharably, Michael Zhen-Yu Tong, Gustavo A Heresi

Abstract read
In one paragraph

Article in JTCVS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Benjamin YangDepartment of Thoracic and Cardiovascular Surgery, Heart Vascular and Thoracic Institute, Cleveland, Ohio.
Anthony ZakiDepartment of Thoracic and Cardiovascular Surgery, Heart Vascular and Thoracic Institute, Cleveland, Ohio.
Nicholas OhDepartment of Thoracic and Cardiovascular Surgery, Heart Vascular and Thoracic Institute, Cleveland, Ohio.
Juan Umana-PizanoDepartment of Thoracic and Cardiovascular Surgery, Heart Vascular and Thoracic Institute, Cleveland, Ohio.
Ihab HaddadinDepartment of Pulmonary Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, Ohio.
Alice GoyanesDepartment of Interventional Radiology, Imaging Institute, Cleveland, Ohio.
Nicholas SmediraDepartment of Thoracic and Cardiovascular Surgery, Heart Vascular and Thoracic Institute, Cleveland, Ohio.
Haytham ElgharablyDepartment of Thoracic and Cardiovascular Surgery, Heart Vascular and Thoracic Institute, Cleveland, Ohio.
Michael Zhen-Yu TongDepartment of Thoracic and Cardiovascular Surgery, Heart Vascular and Thoracic Institute, Cleveland, Ohio.
Gustavo A HeresiDepartment of Pulmonary Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, Ohio.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Chronic thromboembolic pulmonary hypertension (CTEPH) is an under-recognized complication of pulmonary embolism that, if left untreated, leads to heart failure. This study aimed to characterize the role of a multidisciplinary team in the management of CTEPH. Methods: Starting in 2011, a multidisciplinary team was assembled to systematically evaluate and manage all CTEPH patients based on hemodynamic profile, extent of thromboembolic disease burden, and comorbidities. From 1997 to 2021, 306 patients underwent pulmonary thromboendarterectomy for CTEPH. The cohort was divided into an early era prior to 2011 (62 cases) and a recent era from 20,211 to 2021 (244 cases). Results: Baseline demographic and hemodynamic profiles were similar in the 2 eras, with a mean age of 53 ± 14 years, mean pulmonary artery pressure of 44.9 ± 11.2 mm Hg, and mean pulmonary vascular resistance of 7.4 ± 3.9 Wood units. Early era patients had more severe right ventricular dysfunction (49.1% vs 25.0%; Conclusions: Outcomes after pulmonary thromboendarterectomy improved since the establishment of the multidisciplinary team-most notably, more complete resolution of pulmonary hypertension and improved overall survival. A team-based approach for selection and perioperative management of these complex patients can be associated with improved early outcomes.

Indexed as

chronic thromboembolic pulmonary hypertensionheart teampulmonary thromboendarterectomyright heart failure

Identifiers

PMID40309695
PMCPMC12039436

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.