Evidence map›Paper›PMID 40309692›Full record

ArticleJTCVS open2025

Valve-sparing aortic root replacement: Strategies to avoid residual aortic regurgitation.

Fabian A Kari, Martin Czerny, Michael Borger, Martin Misfeld, Emmanuel Zimmer, Matthias Siepe, Christian Hagl, Christian Detter, Johannes Petersen, Doreen Richardt and 5 more

Abstract read
In one paragraph

Article in JTCVS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Fabian A KariDepartment of Cardiac Surgery, LMU University Hospital, Munich, Germany.
Martin CzernyDepartment of Cardiovascular Surgery, Heart Center Freiburg University, Freiburg, Germany.
Michael BorgerDepartment of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
Martin MisfeldDepartment of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney, Australia.
Emmanuel ZimmerDepartment of Cardiovascular Surgery, Inselspital, Bern, Switzerland.
Matthias SiepeDepartment of Cardiovascular Surgery, Inselspital, Bern, Switzerland.
Christian HaglDepartment of Cardiac Surgery, LMU University Hospital, Munich, Germany.
Christian DetterDepartment of Cardiovascular Surgery, University Heart Center Hamburg, Hamburg, Germany.
Johannes PetersenDepartment of Cardiovascular Surgery, University Heart Center Hamburg, Hamburg, Germany.
Doreen RichardtDepartment of Cardiac and Thoracic Vascular Surgery, University Hospital Schleswig-Holstein, Campus Luebeck, Luebeck, Germany.
Stephan EnsmingerDepartment of Cardiac and Thoracic Vascular Surgery, University Hospital Schleswig-Holstein, Campus Luebeck, Luebeck, Germany.
Paul WernerDepartment of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Martin AndreasDepartment of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Maximilian PichlmaierDepartment of Cardiac Surgery, LMU University Hospital, Munich, Germany.
Christoph S MuellerDepartment of Cardiac Surgery, LMU University Hospital, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The study objective was to identify quantitative criteria to avoid residual aortic valve regurgitation after valve-sparing aortic root replacement. Methods: Between 2016 and 2023, 738 adult patients were recruited into the German Aortic Root Repair Registry. A total of 562 patients with datasets on aortic root measurements and tricuspid valve treated with reimplantation valve-sparing aortic root replacement were selected. End points were any grade of residual aortic valve regurgitation and postrepair coaptation height. Tested variables included procedural and anatomic characteristics, including length of cusp margins and geometric cusp heights. Results: The optimal classifier predicting freedom from residual aortic valve regurgitation was cusp coaptation height 8 to 9 mm or more (sensitivity = 0.7-0.8). Annular downsizing alone was not useful to predict residual aortic valve regurgitation ( Conclusions: The target coaptation height after valve-sparing aortic root replacement should exceed 8 to 9 mm. Chances of achieving it can be estimated on the basis of a measurement of cusp quantity. If in doubt when inspecting a valve, numerical criteria can help with surgical decision-making in favor of or against a valve-sparing approach.

Indexed as

aortic root aneurysmaortic valve repairvalve-sparing aortic root replacement

Identifiers

PMID40309692
PMCPMC12039440

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.