Evidence map›Paper›PMID 40309681›Full record

ArticleJTCVS open2025

Postcardiotomy extracorporeal membrane oxygenation after elective, urgent, and emergency cardiac operations: Insights from the PELS observational study.

Silvia Mariani, Alvaro Perazzo, Maria Elena De Piero, Bas C T van Bussel, Michele Di Mauro, Dominik Wiedemann, Sven Lehmann, Matteo Pozzi, Antonio Loforte, Udo Boeken and 30 more

Abstract read
In one paragraph

Article in JTCVS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

40 authors.

Silvia MarianiMaastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands.
Alvaro PerazzoMaastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands.
Maria Elena De PieroMaastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands.
Bas C T van BusselMaastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands.
Michele Di MauroMaastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands.
Dominik WiedemannDepartment of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Sven LehmannLeipzig Heart Center, Leipzig-Klinikum Links der Weser, Bremen, Germany.
Matteo PozziDepartment of Cardiac Surgery, Louis Pradel Cardiologic Hospital, Lyon, France.
Antonio LoforteDivision of Cardiac Surgery, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Udo BoekenDepartment of Cardiac Surgery, Medical Faculty, Heinrich Heine University, Duesseldorf, Germany.
Robertas SamalaviciusII Department of Anesthesiology, Centre of Anesthesia, Intensive Care and Pain Management, Vilnius University Hospital Santariskiu Klinikos, Vilnius, Lithuania.
Karl BounaderDivision of Cardiothoracic and Vascular Surgery, Pontchaillou University Hospital, Rennes, France.
Xiaotong HouCenter for Cardiac Intensive Care, Beijing Institute of Heart, Lung, and Blood Vessels Diseases, Beijing Anzhen Hospital, Beijing, China.
Jeroen J H BungeDepartment of Intensive Care Adults, and Department of Cardiology, Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands.
Kogulan SriranjanDepartment of Intensive Care Medicine, Center of Applied Medical Research, St Vincent's Hospital, Darlinghurst, and University of New South Wales, Sidney, Australia.
Leonardo SalazarDepartment of Cardiology, Fundación Cardiovascular de Colombia, Bucaramanga, Colombia.
Bart MeynsDepartment of Cardiovascular Sciences, University Hospitals Leuven, Leuven, Belgium.
Michael A MazzeffiDepartments of Medicine and Surgery, University of Maryland, Baltimore, Md.
Sacha MatteucciCardiochirurgia Ospedali Riuniti "Umberto I Lancisi Salesi" Università Politecnica delle Marche, Ancona, Italy.
Sandro SpongaDivision of Cardiac Surgery, Cardiothoracic Department, University Hospital of Udine, Udine, Italy.
Graeme MacLarenCardiothoracic Intensive Care Unit, National University Heart Centre, National University Hospital, Singapore.
Claudio RussoCardiac Surgery Unit, Cardiac Thoracic and Vascular Department, Niguarda Hospital, Milan, Italy.
Francesco FormicaDepartment of Medicine and Surgery, University of Parma, Cardiac Surgery Unit, University Hospital of Parma, Parma, Italy.
Pranya SakiyalakDivision of Cardiovascular and Thoracic Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Antonio FioreDepartment of Cardiothoracic Surgery, University Hospital Henri-Mondor, Créteil, Paris, France.
Daniele CamboniDepartment of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany.
Giuseppe Maria RaffaDepartment for the Treatment and Study of Cardiothoracic Diseases and Cardiothoracic Transplantation, IRCCS-ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione); Department of Precision Medicine in Medical Surgical and Critical Area (Me.Pre.C.C.), University of Palermo, Palermo, Italy.
Rodrigo DiazECMO Unit, Departamento de Anestesia, Clínica Las Condes, Las Condes, Santiago, Chile.
I-Wen WangDivision of Cardiac Surgery, Memorial Healthcare System, Hollywood, Fla.
Jae-Seung JungDepartment of Thoracic and Cardiovascular Surgery, Korea University Anam Hospital, Seoul, South Korea.
Jan BelohlavekSecond Department of Internal Medicine, Cardiovascular Medicine General Teaching Hospital and 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
Vin PellegrinoIntensive Care Unit, The Alfred Hospital, Melbourne, Victoria, Australia.
Giacomo BianchiOspedale del Cuore Fondazione Toscana "G. Monasterio", Massa, Italy.
Matteo PettinariDepartment of Cardiovascular Surgery, Ziekenhuis Oost-Limburg, Genk, Belgium.
Alessandro BarboneCardiac Surgery Unit, IRCCS Humanitas Research Hospital, Rozzano, Italy.
José P GarciaIU Health Advanced Heart & Lung Care, Indiana University Methodist Hospital, Indianapolis, Ind.
Kiran ShekarAdult Intensive Care Services, The Prince Charles Hospital, Brisbane, Australia.
Glenn WhitmanCardiac Intensive Care Unit, Johns Hopkins Hospital, Baltimore, Md.
Roberto LorussoMaastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands.
PELS Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Outcomes in cardiac surgery are influenced by surgical priority, with higher mortality in emergency cases. Whether this applies to postcardiotomy venoarterial (VA) extracorporeal membrane oxygenation (ECMO) remains unknown. This study describes characteristics and outcomes of patients undergoing cardiac operations and requiring VA ECMO, stratified by emergency, urgent, or elective operation. Methods: This retrospective multicenter observational study included adults requiring postcardiotomy VA ECMO between 2000 and 2020. Preoperative and procedural characteristics, complications, and survival were compared among the 3 patient groups. The association between emergency surgery and in-hospital survival was investigated through mixed Cox proportional hazard models. Results: The study cohort comprised 1063 patients (52.2%) with elective operations, 445 (21.8%) with urgent operations, and 528 (26%) with emergency operations. Emergency operations included more coronary artery bypass grafting operations (n = 286; 54.2%; Conclusions: One-quarter of postcardiotomy VA ECMOs are implemented after emergency operations. Despite more complications in emergency cases, in-hospital and 5-year survival are comparable between emergency, urgent, or elective operations.

Indexed as

cardiac surgerycardiogenic shockcomplicationsemergencyextracorporeal life supportextracorporeal membrane oxygenation

Identifiers

PMID40309681
PMCPMC12039454

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.