ArticleJTCVS open2025
Quality of life outcomes after robotic-assisted and video-assisted thoracoscopic surgery for early-stage non-small cell lung cancer.
Article in JTCVS open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Perioperative outcomes of extended robotic-assisted thoracic surgery with combined resection of adjacent structures.JTCVS open · 2026Article
- Comparative effectiveness of robotic and video assisted thoracic surgery for lung cancer across key outcomes.iScience · 2026Article
- Biportal-RATS vs. Uniportal-VATS for Lung Resections: A Propensity Score-Matched Analysis from Early Experience.Journal of clinical medicine · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Limited research exists comparing the impacts of robotic-assisted thoracic surgery (RATS) and video-assisted thoracic surgery (VATS) on patients' physical and mental health-related quality of life (QoL). Methods: A prospective cohort of stage IA non-small cell lung cancer (NSCLC) patients in the Initiative for Early Lung Cancer Research on Treatment from Mount Sinai Health System had QoL measured before surgery and at 2, 6, and 12 months post-treatment using the Medical Outcomes Study Short-Form 12 (SF-12), with Physical Component Summary (PCS) and Mental Component Summary (MCS); the Functional Assessment of Cancer Therapy-Lung Cancer Subscale (FACT-LCS); and Patient Health Questionnaire-4 (PHQ-4; for depression/anxiety). A locally weighted smoothing curve was fitted to identify the best interval knot for post-treatment QoL trends. A piecewise linear mixed-effects model was developed to estimate differences in baseline, 2-month, and 12-month QoL scores and rates of change, adjusting for age, sex, race, ethnicity, smoking status, pack-years, nodule size/consistency, comorbidities, and surgical extent. Results: The study cohort comprised 698 patients, including 458 (65.6%) who underwent VATS and 240 (34.4%) who underwent RATS. The RATS group exhibited a more significant initial decline in physical health at 2 months post-surgery but showed significant recovery by 12 months, achieving similar or slightly higher physical scores compared to baseline. No significant differences in mental health scores over time were seen between the groups. Both groups displayed consistent anxiety and depression scores, with significant improvements in anxiety symptoms at the 2-month mark. The RATS group had fewer postoperative complications and conversion to open thoracotomy. Conclusions: RATS and VATS offer similar long-term QoL outcomes for early-stage NSCLC patients, though RATS patients may experience a sharper initial decline in physical health.
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Registered trials
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