Evidence map›Paper›PMID 40309660›Full record

ReviewFrontiers in neuroscience2025

A window into the brain: multimodal MRI assessment of vascular cognitive impairment.

Changjun Ma, Ailian Liu, Jiahui Liu, Xiulin Wang, Fengyu Cong, Ying Li, Jing Liu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. The enigma of vascular dementia: current state and emerging perspectives.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Changjun MaSchool of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian, China.
Ailian LiuDepartment of Radiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Jiahui LiuStem Cell Clinical Research Center, National Joint Engineering Laboratory, Regenerative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Xiulin WangStem Cell Clinical Research Center, National Joint Engineering Laboratory, Regenerative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Fengyu CongSchool of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian, China.
Ying LiStem Cell Clinical Research Center, National Joint Engineering Laboratory, Regenerative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Jing LiuStem Cell Clinical Research Center, National Joint Engineering Laboratory, Regenerative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular cognitive impairment (VCI) encompasses a diverse range of syndromes, including mild cognitive impairment and vascular dementia (VaD), primarily attributed to cerebrovascular lesions and vascular risk factors. Its prevalence ranks second only to Alzheimer's disease (AD) in neuro diseases. The advancement of medical imaging technology, particularly magnetic resonance imaging (MRI), has enabled the early detection of structural, functional, metabolic, and cerebral connectivity alterations in individuals with VCI. This paper examines the utility of multimodal MRI in evaluating structural changes in the cerebral cortex, integrity of white matter fiber tracts, alterations in the blood-brain barrier (BBB) and glymphatic system (GS) activity, alteration of neurovascular coupling function, assessment of brain connectivity, and assessment of metabolic changes in patients with VCI.

Indexed as

diffusion tensor imagingdynamic functional connectivityglymphatic systemresting-state functional MRIstructure–function couplingvascular cognitive impairment

Identifiers

PMID40309660
PMCPMC12040843

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.