ReviewHealth science reports2025
Etiology of Adult Female Acne-Systematic Review.
Review in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Association of baseline peripheral sex hormone profiles and metabolic parameters with recurrence after oral isotretinoin treatment in patients with severe acne.Frontiers in endocrinology · 2026Article
- The Effects of FemmeBalance Supplement on Symptoms of Premenstrual Syndrome: A Four-Cycle Single-Arm Observational Study of a Novel Nutritional Supplement.Life (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Acne vulgaris is a common inflammatory disease of the skin. Acne occurring in > 25 years old is called "adult acne," and it occurs more commonly in women than in men. Purpose: The aim of this study was to examine the recent findings of the connection between genetic factors, hormones and diet with adult female acne. Methods: The study was conducted as a systematic literature review. For the review, data searches were made on the PubMed and Scopus databases. Finally, 20 articles met the inclusion criteria. Results: According to this systematic literature review, several different hormones may be linked to the development of adult acne. Androgens play a particularly important role, as they can stimulate growth of the sebaceous glands and increase the secretion of sebum, thus promoting the formation of skin changes associated with acne. A high glycemic diet increases the secretion of insulin, which in turn causes an increase in the amount of insulin-like growth factor (IGF)-1. IGF-1 increases the growth of the sebaceous gland, sebum production, keratinocyte proliferation and it activates androgen synthesis, thus contributing to acne pathogenesis. Adults with acne have a positive familial history more often than healthy controls, which indicates the genetic nature of adult acne. Conclusion: This literature review highlighted that especially hyperandrogenism, a positive familial history and a high-glycemic diet may be linked to the development of adult acne. Understanding the pathogenesis of adult acne is crucial for effective treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.