ArticleWorld journal of psychiatry2025
Relationship between inflammatory factors, lactic acid levels, acute skin failure, bad mood, and sleep quality.
Article in World journal of psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Development of a predictive model for septic shock-associated acute skin failure using readily available clinical variables.BMC infectious diseases · 2025Article
- Severe anxiety, depression, and sleep disorders worsen prognosis in patients with septic shock.World journal of psychiatry · 2025Article
- Gut-skin-brain axis in people suffering from sepsis with acute skin failure.World journal of psychiatry · 2025Article
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Authors and funding
5 authors.
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Abstract
backgroundThe central link between septic shock and acute skin failure (ASF) is the inflammatory response, which occurs throughout disease progression and can lead to systemic inflammatory response syndrome. Patients often experience bad moods, sleep disorders, and other health issues. Despite recognizing these factors, no studies have examined the correlation between inflammatory factors, lactic acid levels, ASF, mood disturbances, and sleep quality in critically ill patients. We hypothesize that higher levels of inflammatory factors and lactic acid are associated with more severe ASF and poorer mood and sleep quality, which may inform clinical treatment for septic shock and ASF.
aimTo explore the relationship between inflammatory factors, lactic acid levels, the severity of ASF, bad mood, and sleep quality.
methodsThe retrospective study included 150 patients with septic shock from the Second Hospital of Dalian Medical University, categorized into ASF (
resultsThe ASF group had significantly higher levels of CRP (19.60 ± 4.10
conclusionPeripheral blood levels of IL-6, CRP, TNF-α, and lactic acid correlate positively with SMS, MEWS, SAS, SDS, and PSQI in critically ill patients with ASF.
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