ReviewFrontiers in psychiatry2025
Can social isolation alleviate symptoms of anxiety and depression disorders?
Review in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- The Anxious Mind: Examining the Conflicting Relationships Between Distinct Aspects of Social Anxiety and Social Cognition.Behavioral sciences (Basel, Switzerland) · 2026Article
- The psycho-social dual-pathway perspective on healthy aging in digital age-friendly environments: longitudinal evidence from China.BMC geriatrics · 2026Article
- Developing a wellbeing framework for employees working from home within a South African government entity.Frontiers in psychology · 2026Article
- Network analysis of social isolation, loneliness, depression and anxiety among post-discharge rehabilitation patients.Frontiers in psychiatry · 2026Article
- The Relationship Between Anxiety and Employment Status in a German Working-Age Population: Findings on Sex-Specific Prevalence Rates and Associated Factors of Anxiety From the LIFE-Adult-Study.Depression and anxiety · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study examines the complex interplay between social behavior and mental health, focusing on the neurobiological mechanisms underlying human interactions and their alterations associated with anxiety and depression disorders. These conditions are characterized by heightened threat perception, pervasive worry, physiological responses, emotional dysregulation, and maladaptive behaviors. Through narrative review, this study examines both aspects, addressing social isolation as both a risk factor and an avoidance behavior that may provide temporary relief but ultimately perpetuate the clinical condition in the long term. The findings offer valuable insights for clinical practice, emphasizing interventions that enhance cognitive flexibility to foster stable and supportive interpersonal relationships.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.