Evidence map›Paper›PMID 40309189›Full record

ArticleRoyal Society open science2025

Edge-based modelling for disease transmission on random graphs: an application to mitigate a syphilis outbreak.

Sicheng Zhao, Sahar Saeed, Megan Carter, Bradley Stoner, Maggie Hoover, Hugh Guan, Felicia Maria G Magpantay

Abstract read
In one paragraph

Article in Royal Society open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sicheng ZhaoDepartment of Mathematics and Statistics, McMaster University, Hamilton, Ontario, Canada.ORCID https://orcid.org/0009-0000-9741-0548
Sahar SaeedDepartment of Public Health Sciences, Queen's University, Kingston, Ontario, Canada.
Megan CarterDepartment of Public Health Sciences, Queen's University, Kingston, Ontario, Canada.
Bradley StonerDepartment of Public Health Sciences, Queen's University, Kingston, Ontario, Canada.
Maggie HooverKingston Frontenac and Lennox and Addington Public Health, Kingston, Ontario, Canada.
Hugh GuanKingston Frontenac and Lennox and Addington Public Health, Kingston, Ontario, Canada.
Felicia Maria G MagpantayDepartment of Mathematics and Statistics, Queen's University, Kingston, Ontario, Canada.ORCID https://orcid.org/0000-0002-1064-0357

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Edge-based network models, especially those based on bond percolation methods, can be used to model disease transmission on complex networks and accommodate social heterogeneity while keeping tractability. Here we present an application of an edge-based network model to the spread of syphilis in the Kingston, Frontenac and Lennox & Addington region of southeastern Ontario, Canada. We compared the results of using a network-based susceptible-infectious-recovered (SIR) model to those generated from using a traditional mass action SIR model. We found that the network model yields very different predictions, including a much lower estimate of the final epidemic size. We also used the network model to estimate the potential impact of introducing a rapid syphilis point of care test and treatment intervention strategy that has recently been implemented by the public health unit to mitigate syphilis transmission.

Indexed as

epidemiologypercolationsyphilis

Identifiers

PMID40309189
PMCPMC12040449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.