Evidence map›Paper›PMID 40309185›Full record

ArticleRoyal Society open science2025

Energy-based analysis of biochemical oscillators using bond graphs and linear control theory.

Peter Gawthrop, Michael Pan

Abstract read
In one paragraph

Article in Royal Society open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Peter GawthropSystems Biology Laboratory, School of Mathematics and Statistics, University of Melbourne, Melbourne, Victoria 3010, Australia.ORCID https://orcid.org/0000-0002-6029-515X
Michael PanSystems Biology Laboratory, School of Mathematics and Statistics, University of Melbourne, Melbourne, Victoria 3010, Australia.ORCID https://orcid.org/0000-0002-8978-7350

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The bond graph approach has been recognized as a useful conceptual basis for understanding the behaviour of living entities modelled as a system with hierarchical interacting parts exchanging energy. One such behaviour is oscillation, which underpins many essential biological functions. In this paper, energy-based modelling of biochemical systems using the bond graph approach is combined with classical feedback control theory to give a novel approach to the analysis, and potentially synthesis, of biochemical oscillators. It is shown that oscillation is dependent on the interplay between

Indexed as

biochemical oscillatorsbond graphcontrol theoryenergy-based modellingfeedbacksystems biology

Identifiers

PMID40309185
PMCPMC12040473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.