ArticleFrontiers in pediatrics2025
Higher in-hospital proportion of breast milk intake improves brain functional connectivity and neurological assessment in preterm infants.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Preterm infants may face neurodevelopmental challenges linked to altered brain maturation processes. This study aimed to investigate the impact of in-hospital breast milk intake on brain resting-state functional connectivity (rs-FC) and neurological assessment at discharge in preterm infants. Methods: We collected data on breast milk intake from 97 preterm infants, evaluated neurological outcomes using the Amiel-Tison Neurological Assessment (ATNAT), and assessed rs-FC via functional near-infrared spectroscopy (fNIRS). Groups were stratified by breast milk intake proportion (cutoffs of >70% vs. ≤70%; cutoffs of >90% vs. ≤90%), and conducted logistic regression analysis to explore the relationship between rs-FC and neurological assessment. Results: Preterm infants with >70% breast milk intake exhibited significantly higher ATNAT levels ( Conclusion: Higher in-hospital breast milk intake (>70% of total enteral nutrition) improves rs-FC and neurological outcomes in preterm infants, with dose-dependent effects.
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