Evidence map›Paper›PMID 40309035›Full record

ArticleFrontiers in genetics2025

Unveiling the potential impact of RNA m5C methyltransferases NSUN2 and NSUN6 on cellular aging.

Jiale Zhou, Yang Han, Fuxi Ji, Renquan Zhang, Yuru Liang, Xudong Zhao, Ruizhe Hou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiale Zhou *Department of Neurosurgery, China-Japan Union Hospital of Jilin University, Changchun, China.
Yang Han *Laboratory Animal Center, College of Animal Science, Jilin University, Changchun, China.
Fuxi Ji *Department of Critical Care, The Second Hospital of Jilin University, Changchun, China.
Renquan ZhangLaboratory Animal Center, College of Animal Science, Jilin University, Changchun, China.
Yuru LiangLaboratory Animal Center, College of Animal Science, Jilin University, Changchun, China.
Xudong ZhaoLaboratory Animal Center, College of Animal Science, Jilin University, Changchun, China.
Ruizhe HouDepartment of Neurosurgery, China-Japan Union Hospital of Jilin University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NSUN2 and NSUN6, two family members of NOL1/NSUN protein, are mainly responsible for catalyzing the formation of 5-methylcytosine (m5C) in RNA and highly involved in the physiological and pathological processes of many diseases. To investigate the biological functions of NSUN2 and NSUN6, NSUN2

Indexed as

5-methylcytosineagingNSun2NSUN6RNA methylation

Identifiers

PMID40309035
PMCPMC12040966

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.